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- Product Details
|Host species||Mouse (Mus musculus)|
|Species Reactivity||Horse (Equus caballus)|
|Specificity||This antibody binds to Horse ABCB1.|
|Storage||Store at 4°C: short-term (1-2weeks)|
Store at -20°C: long-term and future use
|Purity||> 90% was determined by SDS-PAGE|
|Purification||Purified with Protein A or G affinity chromatography|
|Application Notes||ELISA: 1:1000-1:3000|
Other applications are to be developed. The optimal dilution should be determined by the end user.
|Introduction||The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants.|
|Product Overview||Mouse Anti-Horse ABCB1 (clone MO43542W) Antibody (MO-AB-43542W) is a mouse antibody against ABCB1. It can be used for ABCB1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.|
|Alternative Names||P-glycoprotein; ABCB1|
|Protein Refseq||The length of the protein is296 amino acids long.|
The sequence is show below: NFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSAAHIIMIIEKTPLIDSYSTEGLKPNTLEGNVIFNEVVFNYPTRPDIPVLQGLSVXVKKGQTLALVGSSGCGKSTLVQLLERFYDPMAGTVLLDGTEIKHLNVQWLRAHLGIVSQEPILFDCSIGENIAYGDNSRVVSQEEIVQAAKEANIHPFIETLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGKVKERGTHQQLLAQKG.
See other products for " ABCB1 "
|MO-AB-23442R||Mouse Anti-Pig ABCB1 Antibody (MO-AB-23442R)|
|MO-AB-00013Y||Mouse Anti-Chicken ABCB1 Antibody (MO-AB-00013Y)|
|MO-AB-50184W||Mouse Anti-Marmoset ABCB1 Antibody (MO-AB-50184W)|
|MO-AB-01127H||Mouse Anti-Frog abcb1 Antibody (MO-AB-01127H)|
|CBMOAB-1261FYC||Mouse Anti-Arabidopsis ABCB1 Antibody (CBMOAB-1261FYC)|
|MO-AB-14056Y||Mouse Anti-Sheep Abcb1 Antibody (MO-AB-14056Y)|
|MO-AB-28778W||Mouse Anti-Dog ABCB1 Antibody (MO-AB-28778W)|
|MO-AB-43543W||Mouse Anti-Horse ABCB1 Antibody (MO-AB-43543W)|
|MO-AB-50185W||Mouse Anti-Marmoset ABCB1 Antibody (MO-AB-50185W)|
|MO-AB-28779W||Mouse Anti-Dog ABCB1 Antibody (MO-AB-28779W)|