Cat: MO-AB-43543W
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Horse (Equus caballus) |
| Clone | MO43543W |
| Specificity | This antibody binds to Horse ABCB1. |
| Format | Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. |
| Product Overview | Mouse Anti-Horse ABCB1 (clone MO43543W) Antibody (MO-AB-43543W) is a mouse antibody against ABCB1. It can be used for ABCB1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | P-glycoprotein; ABCB1 |
| UniProt ID | V5REV0 |
| Protein Refseq | The length of the protein is296 amino acids long. The sequence is show below: NFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSAAHIIMIIEKTPLIDSYSTEGLKPNTLEGNVIFNEVVFNYPTRPDIPVLQGLSVEVKKGQTLALVGXSGCGKSTLVQLLERFYDPMAGTVLLDGTEIKHLNVQWLRAHLGIVSQEPILFDCSIGENIAYGDNSRVVSQEEIVQAAKEANIHPFIETLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPQILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGKVKERGTHQQLLAQKG. |
See other products for " ABCB1 "
| MO-AB-06751R | Mouse Anti-Cattle ABCB1 Antibody (MO-AB-06751R) |
| MO-AB-28778W | Mouse Anti-Dog ABCB1 Antibody (MO-AB-28778W) |
| MO-AB-01127H | Mouse Anti-Frog abcb1 Antibody (MO-AB-01127H) |
| MO-AB-23442R | Mouse Anti-Pig ABCB1 Antibody (MO-AB-23442R) |
| MO-AB-06752R | Mouse Anti-Cattle ABCB1 Antibody (MO-AB-06752R) |
| MO-AB-14056Y | Mouse Anti-Sheep Abcb1 Antibody (MO-AB-14056Y) |
| MO-AB-10588Y | Mouse Anti-O. mykiss Abcb1 Antibody (MO-AB-10588Y) |
| MO-AB-43544W | Mouse Anti-Horse ABCB1 Antibody (MO-AB-43544W) |
| MO-AB-30556H | Mouse Anti-Purple sea urchin ABCB1 Antibody (MO-AB-30556H) |
| CBMOAB-34801FYA | Mouse Anti-Rhesus ABCB1 Antibody (CBMOAB-34801FYA) |
For Research Use Only | Not For Clinical Use.