Mouse Anti-Horse ATRX Antibody (MO-AB-43824W)
Cat: MO-AB-43824W
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Horse (Equus caballus) |
| Clone | MO43824W |
| Specificity | This antibody binds to Horse ATRX. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Product Overview | Mouse Anti-Horse ATRX Antibody is a mouse antibody against ATRX. It can be used for ATRX detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Transcriptional regulator ATRX-like protein; ATRX |
| UniProt ID | L7MS78 |
| Protein Refseq | The length of the protein is321 amino acids long. The sequence is show below: NRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSSGLSSKPENCGLGQEKNDELLVESEVPLLSEESDLRRSPRVKTTPLRRQTETNPATSNSDEESNETVKEKQKLAVQMRKKDRRNSSDSALDNPKPNKLPKSKQSEIMDQNSDSDEMLAILKEVSRMSHGSSSDTDINETHTSHEKTLYDLKTQSGKDDKGKRKRKSSTSSSDFDIKKGKSAKRSMISKKKRENRSESSNYDSELEKEIKSMSKIGAARTTKKRVPNNEDYDSSEDEKQRNKGMDNQGQKSLKTAQEGSSDDAERKQRERISLQ. |
See other products for " ATRX "
| MO-AB-51627W | Mouse Anti-Marmoset ATRX Antibody (MO-AB-51627W) |
| CBMOAB-24911FYC | Mouse Anti-Arabidopsis ATRX Antibody (CBMOAB-24911FYC) |
| CBMOAB-36624FYA | Mouse Anti-Rhesus ATRX Antibody (CBMOAB-36624FYA) |
| CBMOAB-67209FYA | Mouse Anti-Zebrafish atrx Antibody (CBMOAB-67209FYA) |
| MO-AB-25136W | Mouse Anti-Chimpanzee ATRX Antibody (MO-AB-25136W) |
| MO-AB-24275H | Mouse Anti-Rat Atrx Antibody (MO-AB-24275H) |
| MO-AB-27160W | Mouse Anti-Chimpanzee ATRX Antibody (MO-AB-27160W) |
| MO-AB-01218W | Mouse Anti-Rhesus ATRX Antibody (MO-AB-01218W) |
For Research Use Only | Not For Clinical Use.
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