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- Product Details
|Host species||Mouse (Mus musculus)|
|Species Reactivity||Horse (Equus caballus)|
|Specificity||This antibody binds to Horse CD44.|
|Storage||Store at 4°C: short-term (1-2weeks)|
Store at -20°C: long-term and future use
|Purity||> 90% was determined by SDS-PAGE|
|Purification||Purified with Protein A or G affinity chromatography|
|Cellular Localization||Plasma membrane; Other locations|
|Application Notes||ELISA: 1:1000-1:3000|
Other applications are to be developed. The optimal dilution should be determined by the end user.
|Introduction||Cell-surface receptor that plays a role in cell-cell interactions, as well as cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases. Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.|
|Product Overview||Mouse Anti-Horse CD44 (clone MO44003W) Antibody (MO-AB-44003W) is a mouse antibody against CD44. It can be used for CD44 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.|
|Alternative Names||CD44 antigen; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing / adhesion receptor; HUTCH-I; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I; CD antigen CD44; CD44|
|Protein Refseq||The length of the protein is359 amino acids long.|
The sequence is show below: MDKFWWRAAWGLCLVPLSLAQIDLNITCRYAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMQKALNIGFETCRIGFIEGHVVIPPIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFEGPITITIVNRDGTRYTKKGEYRTNPEDINPSTPADDDVSSGSSSERSTSGGYSIFHTHLPTTRPTQDQSSPWVSDSPEKTPTTKDRASGGRAQTTHGSETSGHSTGSQEGGASTTSGPIRRPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINNGNGAVDDRKASGLNGEASRSQEMVHLVNKESSETQDQFMTADETRNLQNVDMKIGV.
See other products for " CD44 "
|MO-AB-44002W||Mouse Anti-Horse CD44 Antibody (MO-AB-44002W)|
|MO-AB-09841R||Mouse Anti-Cattle CD44 Antibody (MO-AB-09841R)|
|MO-AB-52567W||Mouse Anti-Marmoset CD44 Antibody (MO-AB-52567W)|
|MO-AB-09840R||Mouse Anti-Cattle CD44 Antibody (MO-AB-09840R)|
|MO-AB-09839R||Mouse Anti-Cattle CD44 Antibody (MO-AB-09839R)|
|MO-AB-09843R||Mouse Anti-Cattle cd44 Antibody (MO-AB-09843R)|
|MO-AB-03488W||Mouse Anti-Rhesus CD44 Antibody (MO-AB-03488W)|
|MOFY-0522-FY23||Mouse Anti-CD44 Antibody (MOFY-0522-FY23)|
|CBMOAB-38713FYA||Mouse Anti-Rhesus CD44 Antibody (CBMOAB-38713FYA)|
|MO-AB-14937W||Mouse Anti-Chimpanzee CD44 Antibody (MO-AB-14937W)|