Mouse Anti-Hsp60 Antibody (MOFAB-114W)
Cat: MOFAB-114W
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- Product Details
Specifications
Host species | Mouse |
Species Reactivity | Human, Mouse, Rat, Rabbit, Bovine, Danine, Porcine, Ovine, Guinea Pig, Hamster, Chicken, Monkey, Xenopus, Drosophila |
Clone | WLK |
Specificity | This antibody recognizes human, mouse, rat, rabbit, bovine, canine, porcine, sheep, guinea pig, hamster, chicken, monkey, Xenopus and Drosophila Hsp60 (60 kDa). It does not cross-react with bacterial or yeast Hsp60. The recognized epitope is within aa 383-447 of human Hsp60. |
Immunogen | Recombinant human Hsp60 expressed in E. coli. |
Format | Liquid or Lyophilized |
Buffer | PBS, pH 7.4, 50% glycerol |
Regulatory Status | For Research Use Only |
Shipping | Gel Pack |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Protein G |
Application Information
Application | WB, IP, FC |
Application Notes | IB: 0.1-1ug/ml IP: 12.5ug/ml FC: 10ug/ml The optimal dilution should be determined by the end user. |
Target
Introduction | Hsp60 is an abundant protein that is constitutively synthesized in various cell types and is induced to higher concentrations after cellular shock. It is present in the mitochondria of many mammalian species and has highly similar counterparts in bacteria and plants (it is localized to the chloroplast). In general, Hsp60 proteins are present in high concentrations, are induced in response to environmental stress (such as heat shock), are homo-oligomeric structures of 7 or 14 subunits, dissociate reversibly in the presence of Mg2+ and ATP, have ATP Enzymatic activity, and plays a role in the folding and assembly of oligomeric protein structures. Hsp60 has been implicated in Alzheimer's disease, coronary artery disease, multiple sclerosis, diabetes and other autoimmune diseases. |
Product Overview | The Hsp60 antibody is used as Heat Shock and Stress Protein Antibodies. |
Alternative Names | Protein HSP-60, isoform b; hsp-60; Hsp60 |
See other products for " Hsp60 "
MOFAB-119W | Rabbit Anti-Hsp60 Antibody (MOFAB-119W) |
CBMOAB-01764CR | Mouse Anti-Yeast HSP60 Antibody (CBMOAB-01764CR) |
CBMOAB-05167HCB | Mouse Anti-C. elegans HSP60 Antibody (CBMOAB-05167HCB) |
MO-AB-23289H | Mouse Anti-Mallard HSP60 Antibody (MO-AB-23289H) |
CBMOAB-20820FYA | Mouse Anti-D. melanogaster Hsp60 Antibody (CBMOAB-20820FYA) |
For Research Use Only | Not For Clinical Use.
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