Goat Anti-IDH1 Antibody
Cat: MO-NAB-00514W
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- Product Details
Specifications
| Host species | Goat (Capra hircus) |
| Species Reactivity | Yeast, S. cerevisiae (Saccharomyces cerevisiae) |
| Clone | NW0436 |
| Specificity | This antibody is binds to Yeast IDH1 and has cross reactivity with S. cerevisiae. |
| Immunogen | The peptide with the sequence C-EPGSRHVGLDIKGQN comes from the internal region of the protein sequence according to NP_014361.1. |
| Format | Liquid or Lyophilized |
| Buffer | 0.5 mg/ml in Tris saline, pH7.3, 0.5% BSA. |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | Pep-ELISA, WB |
Target
| Introduction | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Product Overview | This product is a Goat antibody against the IDH1. It can be used for IDH1 detection in Pep-Enzyme-Linked Immunosorbent Assay, Western Blot. |
| Alternative Names | Isocitrate Dehydrogenase (NADP(+)) 1, Cytosolic |
| Gene ID | 3417(Human); 15926(Mouse); 24479(Rat) |
| UniProt ID | O75874(Human); O88844(Mouse); P41562(Rat) |
See other products for " IDH1 "
| MO-AB-24006W | Mouse Anti-Chimpanzee IDH1 Antibody (MO-AB-24006W) |
| CBMOAB-05230HCB | Mouse Anti-C. elegans IDH1 Antibody (CBMOAB-05230HCB) |
| MO-AB-57103W | Mouse Anti-Marmoset IDH1 Antibody (MO-AB-57103W) |
| MO-AB-38586W | Mouse Anti-Gorilla IDH1 Antibody (MO-AB-38586W) |
| MO-DKB-01757W | Rabbit Anti-IDH1 Antibody (MO-DKB-01757W) |
| CBMOAB-01822CR | Mouse Anti-Yeast IDH1 Antibody (CBMOAB-01822CR) |
| MO-AB-31214W | Mouse Anti-Dog IDH1 Antibody (MO-AB-31214W) |
| MO-AB-06561Y | Mouse Anti-O. anatinus IDH1 Antibody (MO-AB-06561Y) |
| MO-AB-13940R | Mouse Anti-Cattle IDH1 Antibody (MO-AB-13940R) |
| MO-AB-41844W | Mouse Anti-Guinea pig IDH1 Antibody (MO-AB-41844W) |
For Research Use Only | Not For Clinical Use.
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