Cat: MOFAB-323W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product Details
Specifications
| Host species | Mouse |
| Species Reactivity | Cow, Dog, Horse, Human, Non-human primate, Pig, Sheep |
| Clone | WMT504 |
| Specificity | Native and recombinant IL-17A. |
| Format | Liquid |
| Buffer | PBS |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
Application Information
| Application | ELISA, ELISpot, FC |
| Application Notes | The optimal dilution should be determined by the end user. |
Target
| Introduction | IL-17A (IL-17A, IL17A) is a potent pro-inflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8+ T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and resistance to bacteria and fungi. IL-17A acts on a wide range of cell types to induce the expression of cytokines, chemokines and metalloproteinases. Therefore, secretion of IL-17A promotes the inflammatory response, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased IL-17A expression is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It has also been linked to asthma, psoriasis, cancer and transplant rejection. |
| Product Overview | The IL-17A antibody is used as Veterinary research antibodies. |
| Alternative Names | Interleukin-17A/F-1; IL-17A/F-1; human IL-17A |
See other products for " IL-17A "
| MOFAB-340W | Mouse Anti-IL-17A Antibody (MOFAB-340W) |
| MO-AB-00749R | Mouse Anti-Medaka IL-17A Antibody (MO-AB-00749R) |
| MO-AB-00751R | Mouse Anti-Medaka IL-17A Antibody (MO-AB-00751R) |
| MOFAB-324W | Mouse Anti-IL-17A Antibody (MOFAB-324W) |
| MOFAB-339W | Mouse Anti-IL-17A Antibody (MOFAB-339W) |
| MO-AB-00750R | Mouse Anti-Medaka IL-17A Antibody (MO-AB-00750R) |
For Research Use Only | Not For Clinical Use.