Mouse Anti-IL12RB2 Antibody (CBMOAB-45249FYA)


Cat: CBMOAB-45249FYA
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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-45249FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Donkey (Equus asinus), Pig (Sus scrofa), Sheep (Ovis aries), Zebrafish (Danio rerio) WB, ELISA MO45249FYA 100 µg
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CBMOAB-80589FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO80589FYA 100 µg
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MO-AB-02451Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO02451Y 100 µg
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MO-AB-14104R Monoclonal Cattle (Bos taurus) WB, ELISA MO14104R 100 µg
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MO-AB-15752Y Monoclonal Sheep (Ovis aries) WB, ELISA MO15752Y 100 µg
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MO-AB-26631R Monoclonal Pig (Sus scrofa) WB, ELISA MO26631R 100 µg
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MO-AB-34249W Monoclonal Donkey (Equus asinus) WB, ELISA MO34249W 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Chicken (Gallus gallus), Donkey (Equus asinus), Pig (Sus scrofa), Sheep (Ovis aries), Zebrafish (Danio rerio)
CloneMO45249FYA
SpecificityThis antibody binds to Rhesus IL12RB2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene. (From NCBI)
Product OverviewMouse Anti-Rhesus IL12RB2 Antibody is a mouse antibody against IL12RB2. It can be used for IL12RB2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesIL12RB2
UniProt IDF6X0C8
Protein RefseqThe length of the protein is 863 amino acids long.
The sequence is show below: MAHTFRRCSLALIFITMWLLIKAKIDECKRGDVTVKPSRVILLGSTVNISCSLKPRQGCSPYSRRNKLILYKFDRRINFHHGHSLNAQVTGLPLGTTLFVCKLACINSDEIQICGAEILVGVAPEQPQNLSCIQKGEQGTVACTWERGQDTHLYTEYTLQLSGPKNLTWQKQCKDHYCDYLDFGINLTPESPESNFTAKVTAVNSLGSSSSFPSTFTFLDIVRPLPPWDIRIKFQKASSVSRCTLYWRDEGLVLLNRLRYRPSNSRHWNMVNVTEARGRHDLLDLKPFTEYEFQISSKLHLYKGSWSDWSETLRAQTPEEEPTGMLDVWYMKRHIDYSRQQISLFWKNLSVSEARGKILHYQVTLQELTGGKVMTQNITGHTSWTTVISRTGNWAVAVSAANSKGNSLPTRINIMNLCEAGLLAPHQVSANSESMDSILVTWQPPRKDLSAVQEYVVEWRQLHPGDDTQIPLNWLRSPPYNVSALISENIKPYTCYEIRVYALSEDQGGCSSILGNSKHKAPLSGPHINAITEEKGSILISWNSIPVQEQMGCLLHYRIYWKERDSNSQPQLCEIPYRVSQNSHPINSLQPRVTYVLWMTALTAAGESSQGNEREFCLQGKANWMAFVAPSICVAIIMVGIFSTHYFQQKLSVFLAALRPQWCSREIPDPANSTCTKKYPTAEEKTQLPLDRLLIDWSMPEDPEPLVISEVFHQVTPIVRRPHCSNWPQRGKGIQGHQASEKDMMHSASSPPPPRALPAESRQLVDLYKVLESRGSYPKPENPASPWTVLPAGNLPTHDGYLPSNIDDLPSHEVPLTDSLEELEPQHISLSVFPSSSLHPLTFSYGDKLTLDQLKMRCDSLML.
For Research Use Only | Not For Clinical Use.
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