Mouse Anti-IREB2 Antibody (CBMOAB-45551FYA)

Cat: CBMOAB-45551FYA

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-45551FYA	Monoclonal	Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO45551FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 959 amino acids long. The sequence is show below: SGYAFEYLIETLNDSSHKKFFDVSKLGGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQVNLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQRDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLHVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKNIYLHDIWPSREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPVALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS.
CBMOAB-81072FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO81072FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 974 amino acids long. The sequence is show below: MALGSLQNEHPYGHLIDTLQSEQYQEQKYFSPQKLNDVRYEKLPFCMRVLLESAIRKCDEFYVKTEDVSSILDWQVQQNQAEVVFSPARVLLQDFTGIPAMVDLAAMRDALAKQGVDPSLVNPRCPTDLIVDHSLQIDYSKCGIQSPPASVDESPTVKSPAGRPSPRVSSSSGHCSGQRSGHRGGCSKPSCSDAPGGRTAAVQIENTPLLCPFHLQPVSEPETMVRNQEMELIRNKERLQFFKWCSKSFNNVNVVPPDISTVHQLNLEYLCKVVQEEEGFIYPDSVVGTDSHTTMINGLGILGWGVGGIESEAVMLGQPVSLTLPQVVGCKLVGTINPLATSIDIVLGITKHLRQAGIGGKFVEFFGPGVPQLSAPDRTTIANMCPEYNATVSFFPVDDITLQHFKHTICSEEKLLVLEDYLKAVKLFRSYDDQSEEPQYSEVIEMNLSSIVPHVSGPKRPQDRVAITGMKEDFISCLNEKVGFKGFHISKEKQSTLVPFRHDGAEYNLAHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLTVKPYIRTSLVPGSGTVTHYLNTSGVLPFLKKLGFEVVGYGCATCVGNTAPLPESVVDAVKQGDLVACGVLSGNRHLEGRLCDCVRANYLASPPLVVAYAIAGTVSINLETEPLGVNADGKDVFLCDIWPTKEEVNHIEENIVIASMFTELRSRMEKGSSFWNNLESAESALFPWDPKSTYIRCPSFFSKMSKEVCSPQSIDGAYPLLFLGDKVTTDHISPAGSIARVSAAAKYLQSKRLTPREFNSYGARRGNDAVMTRGTFASIKLQNRLIGKTGPKTLHIPTGQTLDVFEAAERYQRDGVPLIILAGKEYGSGSSRDWAAKGPYLLGVRAVIAESFEKIHRNHLVGMGIAPLQFLPGQNADSLELCGKERFTIDIPEELTARQQITVQTSTGKSFMVTALFENDMDVEFFRHGGILKYVARSLLP.
MO-AB-14638W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO14638W		100 µg	Inquiry
Protein Refseq: The length of the protein is 963 amino acids long. The sequence is show below: MDAPTAGYAFEYLIETLNDSSRKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMTKEDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQKDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGDLVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIYLHDIWPSREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS.
MO-AB-57363W	Monoclonal	Marmoset	WB, ELISA	MO57363W		100 µg	Inquiry
Protein Refseq: The length of the protein is 964 amino acids long. The sequence is show below: MDAPKAGYAFEYLIETLNDSSHKKFFNVSKLGGTKYDALPYSIRVLLEAAVRNCDGFFMKKEDVVNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRNSGTFPSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQVNLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLILPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIADRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQKDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLHVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGILSGNKNFEGRLCDCVRASYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIYLNDIWPSREEVHRVEEEHVILSMFKALKEKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPVALQPIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLMNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGFGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELAPGITLNIQTSTGKVFSVIASFENDVEITLYKHGGLLNFVARKFS.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio)
Clone	MO45551FYA
Specificity	This antibody binds to Rhesus IREB2.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Other locations; Cytosol

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	The protein encoded by this gene is an RNA-binding protein that acts to regulate iron levels in the cells by regulating the translation and stability of mRNAs that affect iron homeostasis under conditions when iron is depleted. When iron levels are low, this protein binds to iron-responsive elements (IRES), stem-loop structures located either in the 5' or 3' UTRs. Binding to the 5' UTR represses translation, while binding to the 3' UTR inhibits mRNA degradation. When iron is found in the cell, this protein is degraded in a F-box and leucine rich repeat protein 5-dependent manner. Variants in this gene have been associated with lung cancer and chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Overview	Mouse Anti-Rhesus IREB2 Antibody is a mouse antibody against IREB2. It can be used for IREB2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	IREB2
UniProt ID	F7E7R2
Protein Refseq	The length of the protein is 959 amino acids long. The sequence is show below: SGYAFEYLIETLNDSSHKKFFDVSKLGGTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPKKVHPACPTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIPPGTGMAHQVNLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQRDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLHVKPYIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSEAVLNAVKQGDLVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDSTGKNIYLHDIWPSREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDKLTKEPVALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSGRETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS.

For Research Use Only | Not For Clinical Use.

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