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Rabbit Anti-ITGAM Antibody (MO-DKB-00397W)


Cat: MO-DKB-00397W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Bovine (Bos taurus), C. elegans (Caenorhabditis elegans), Chinese Hamster, Primat, Rhesus (Macaca mulatta)
ImmunogenSynthetic peptide in the inner region of the mouse CD11b protein.
EpitopeThe epitope is in the AA 250-350 of ITGAM.
FormatLiquid
BufferPBS
StorageAliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
PurityAffinity purified
Cellular LocalizationMonocytes and granulocytes

Application Information

ApplicationWB, Simple Western, FC, IF, IHC, IHC-Fr, IHC-P, ISH, Dual ISH-IHC, Single-Cell Western
Application NotesWestern Blot 2 ug/mL
Simple Western 1:50
Flow Cytometry 1:10-1:1000
Immunocytochemistry/Immunofluorescence 1:200
Immunohistochemistry 1:400
Immunohistochemistry-Frozen
Immunohistochemistry-Paraffin 1:400
In-situ Hybridization
Dual RNAscope ISH-IHC
Single Cell Western 1:10

Target

IntroductionThis gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Product OverviewThis product is a Rabbit antibody against the AA 250-350 of the ITGAM. It can be used for ITGAM detection in Western Blot, Simple Western, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, ISH, Dual ISH-Immunohistochemistry, Single-Cell Western.
Alternative NamesIntegrin Subunit Alpha M
Gene ID3684
UniProt IDP11215
For Research Use Only | Not For Clinical Use.

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