Mouse Anti-ITGAX Antibody (MOFY-0522-FY48)


Cat: MOFY-0522-FY48
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Specifications

Host speciesMouse
Species ReactivityHuman, Rhesus, Cynomolgus
ImmunogenRheumatoid synovial cells and human monocytes
FormatLiquid or Lyophilized
BufferBBS, pH 8.2
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationFC, IHC, IP, BL
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Alternative NamesIntegrin Subunit Alpha X
Gene ID100427850(Rhesus)
For Research Use Only | Not For Clinical Use.
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