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Rabbit Anti-KRT13 Antibody (AA 110-160)


Cat: MO-NAB-00410W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Zebrafish (Danio rerio)
CloneNW0335
SpecificityThis antibody is binds to Human KRT13 and has cross reactivity with Mouse, Zebrafish.
ImmunogenSynthetic peptide within 13 aa 110-160 of human cytokeratin.
EpitopeThe epitope is in the AA 110-160 of KRT13.
FormatLiquid
BufferTBS, pH7.4, 1% BSA, 40% Glycerol.
StorageStore at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PurificationProtein A purified
Cellular LocalizationExtracellular exosome; intermediate filament cytoskeleton; keratin filament; nucleus

Application Information

ApplicationWB, IF, IHC, IHC-P
Application NotesWestern Blot: 1:500-1:2000
Immunofluorescence: 1:50-1:200
Immunohistochemistry-Paraffin: 1:50-1:200

Target

IntroductionThe protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described.
Product OverviewThis product is a Rabbit antibody against the AA 110-160 of the KRT13. It can be used for KRT13 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesKeratin 13; Keratin, Type I Cytoskeletal 13; Keratin 13, Type I; Cytokeratin 13; CK-13; K13
Gene ID3860(Human); 16663(Mouse)
UniProt IDP13646(Human); P08730(Mouse)
For Research Use Only | Not For Clinical Use.

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