Mouse Anti-KRT13 Antibody (MOFY-0522-FY84)


Cat: MOFY-0522-FY84
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Specifications

Host speciesMouse
Species ReactivityHuman, Zebrafish
Immunogen1C7 reacts only with cytokeratin 13 present in non-keratinizing squamous epithelial cells, with the exception of the cornea and transitional epithelial regions, with the exception of the basal cell layer of some stratified epithelial cells.
FormatLiquid or Lyophilized
BufferPBS
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationIHC, IHC-Fr, WB
Application NotesImmunohistochemistry: 1:25-1:200
Western Blot: 1:100-1:1000
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This type I cytokeratin is paired with keratin 4 and expressed in the suprabasal layers of non-cornified stratified epithelia. Mutations in this gene and keratin 4 have been associated with the autosomal dominant disorder White Sponge Nevus. The type I cytokeratins are clustered in a region of chromosome 17q21.2. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been described. [provided by RefSeq, Jul 2008]
Alternative NamesKeratin 13; Keratin, Type I Cytoskeletal 13; Keratin 13, Type I; Cytokeratin 13; CK-13; K13;
Gene ID3860
UniProt IDP13646
For Research Use Only | Not For Clinical Use.
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