Anti-m6A Antibody (Cat MO-MMB-0682), Mouse IgG1, kappa


Cat: MO-MMB-0682
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityBudding Yeast, Human (Homo sapiens)
CloneM17-3-4-1
ImmunogenThe antibody is raised against 6-methyladenosine conjugated to BSA.
FormatLiquid
BufferPBS, 30% glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PurificationProtein A purified

Application Information

ApplicationRIP, DB, IF
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionN6-methyladenosine (m6A)) is an RNA modification at the N-6 position of adenosine. It has been found that this modification is abundant in the 3'UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites, indicating a potential role in epigenetic gene regulation. FTO and ALKBH are 6-methyladenosine demethylases, and the polyprotein complex containing METTL3 functions as a methyltransferase. Recent research results indicate that m6A also exists on metazoan DNA, indicating that this modification also has a true epigenetic effect in the DNA environment.
Alternative Namesm6A; N6-Methyladenosine
For Research Use Only | Not For Clinical Use.

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