Cat: MO-MMB-0682
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Budding Yeast, Human (Homo sapiens) |
| Clone | M17-3-4-1 |
| Immunogen | The antibody is raised against 6-methyladenosine conjugated to BSA. |
| Format | Liquid |
| Buffer | PBS, 30% glycerol |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Purification | Protein A purified |
Application Information
| Application | RIP, DB, IF |
| Application Notes | The optimal dilution should be determined by the end user. |
Target
| Introduction | N6-methyladenosine (m6A)) is an RNA modification at the N-6 position of adenosine. It has been found that this modification is abundant in the 3'UTR and stop codons of mammalian mRNA. m6A is associated with miRNA binding sites, indicating a potential role in epigenetic gene regulation. FTO and ALKBH are 6-methyladenosine demethylases, and the polyprotein complex containing METTL3 functions as a methyltransferase. Recent research results indicate that m6A also exists on metazoan DNA, indicating that this modification also has a true epigenetic effect in the DNA environment. |
| Alternative Names | m6A; N6-Methyladenosine |
For Research Use Only | Not For Clinical Use.