Cat: MO-AB-22831H
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Mallard (Anas platyrhynchos) |
Clone | MO22831C |
Specificity | This antibody binds to Mallard ALAD. |
Format | Lyophilized |
Storage | Store at 4°C: short-term (1-2 weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. |
Product Overview | This product is a mouse antibody against ALAD. It can be used for ALAD detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Delta-aminolevulinic acid dehydratase; EC 4.2.1.24; ALAD |
UniProt ID | U3IHZ7 |
Protein Refseq | The length of the protein is 268 amino acids long. The sequence is show below: PKMQADSLLHSGYFHPVLRSWQCTASTFDASNLIYPIFVTDSPDAVEPIASLPGQARYGVNKLEGMLRPLVEDSLKCVLIFGVPSKVPKDERGSAADAEDTPAIQAIKKIRSTFPELLIACDVCLCPYTSHGHCGILREDGTIQNELSCQRLAEVALAYAKAGCHIVAPSDMMDGRIAAIKQALISNDMGNKVSVMSYSAKFASCFYGPFRDAAQSKPAFGDRRCYQLPPGARGLGLRAVDRDVREGADMLMVKPGMPYLDLVRDVKN. |
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For Research Use Only | Not For Clinical Use.