Mouse Anti-Marmoset BAG3 Antibody (MO-AB-51717W)


Cat: MO-AB-51717W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset
CloneMO51717W
SpecificityThis antibody binds to Marmoset BAG3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionBAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
Product OverviewMouse Anti-Marmoset BAG3 Antibody is a mouse antibody against BAG3. It can be used for BAG3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesBAG family molecular chaperone regulator 3; BAG3
UniProt IDU3BXN6
Protein RefseqThe length of the protein is 574 amino acids long.
The sequence is show below: MSAATHSPMMQVASGNGDRDPLPPGWEIKIDPQTGWPFFVDHNSRTTTWNDPRVPPEGPKETSSSANGPSREGSRLLPAREGHPVYPQLRPGYIPIPVLHEGTENRQPHPFHAYPQPGMQRFRTEAAAAAPQRSQSPQRGMPETTQLDKQCGQVAAAAAVQPPASHGLERSQSPAASDCSSSSSSASLPSSGRSSLGSHQLPRGYISIPVIHEQNITRPAAQPSFHQAQKMHYPAQQGEYQTHQPVYHKIQGDDWEPRPLRAASPFRSPVQSASSREGSPARSSTPLHSPSPIRVHTVVDRPQQPMTHQESAPIPQPENKPESKPGPVGPDLPPGHVPIQVIRKEVDSKPVSQKPPPPSEKVEVKVPPAPVPCPSPSPGPSAVPSSPKNVATEERAAPSTAPAEATPPKPGEDEAPPKHPGVLKVEAILEKVQGLEQAVDNFEGKKTDKKYLMIEEYLTKELLALDSVDPEGRADVRQARRDGVRKVQTILEKLEQKAIDVPGQVQVYELQPGSLEADQPLQAIMEMGAMAADKGKTNAGSGEDPHTETQQPEAAAAASNPSSTTDTTGNPAAP.
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For Research Use Only | Not For Clinical Use.
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