Mouse Anti-Marmoset BAP1 Antibody (MO-AB-51743W)


Cat: MO-AB-51743W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset
CloneMO51743W
SpecificityThis antibody binds to Marmoset BAP1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma.
Product OverviewMouse Anti-Marmoset BAP1 Antibody is a mouse antibody against BAP1. It can be used for BAP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesUbiquitin carboxyl-terminal hydrolase; EC 3.4.19.12; BAP1
UniProt IDU3FPA9
Protein RefseqThe length of the protein is 729 amino acids long.
The sequence is show below: MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKPASNKSPLVLEAHRVPVASEGTHTDGAEEVAGSCTQAPTHSPPSKPKLVVKPPGSSLNGAPPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVCPPQQYSDDEDDYDDDEEDDVQNTSSAIRYKRKGTGKPGALSSSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGLVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ.
For Research Use Only | Not For Clinical Use.
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