Mouse Anti-MBD6 Antibody (CBMOAB-36276FYC)

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-36276FYC	Monoclonal	A. thaliana (Arabidopsis thaliana), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta), Zebrafish (Danio rerio)	WB, ELISA	MO36276FC		100 µg	Inquiry
Protein Refseq: The length of the protein is 225 amino acids long. The sequence is show below: MSDSVAGDFPPDPLLASGAFISSAGDGTLDSSAKRRPIQGGIGISGSGESVRIGMANGTDQVNHQTESKSRKRAAPGDNWLPPGWRVEDKIRTSGATAGSVDKYYYEPNTGRKFRSRTEVLYYLEHGTSKRGTKKAENTYFNPDHFEGQGSNRVTRTATVPPPPPPPLDFDFKNPPDKVSWSMANAGEEGWIPNIGDVKVQDSVRRDWSTAFTFITSRNPSKVSA.
CBMOAB-50944FYA	Monoclonal	Rhesus (Macaca mulatta)	WB, ELISA	MO50944FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 881 amino acids long. The sequence is show below: MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPKVFNFDPLAPVTLGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPPASQAFPTLAGPGGLFPPRLPDPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPATQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAPVPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQSSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLAGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAASLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPGLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPG.
CBMOAB-86166FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO86166FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 1320 amino acids long. The sequence is show below: MTGGSESVAGEKDGGTTLIAQVPVGWRRKVEDGAVSYISPSGTVLQSVDEVRVYLRTDGTCKCGLECPLVPNKVFNFDPAAMVQAPGHQSGKVEEDMTKLCNHRRKVDAMTALCQSMHPSHLAPLAQATGGVVCSVDGRESRGSMLTHGDGAHCTYPQPRHSQPKPNMGFPLSSSRSVLQNGSVNLSPISRPPDQGSPLKKSQAPVYAKQQWSPHPPLIQNTPQRTAHNPTSPNNVKPTQAHPPDSINSFSFSSSLSNRTIPPMSQGASVKSPSPLSPSRTRDSFSPHQRSRHSSTSSLSDHQIFIQGAKPLHPTMPCSSPKLPNAPLSPCSRLEGILQHYKDCSTSSSISTSANQSIHQASLVALPNASDKRNGAMLGQILNQKQKSHINNSFPASSLLSAAAKAQLANQKTEGLSALPLAGLDKEQQSKVLISTLNSSVHNTSSRPQALTALLLPHSPASPSEKNLRRKRQRRSPTVLSMLKDTQLGRTVLDLSSPPQLIPPCSSPPVHNSSDNLRLPVNPPNCRLQDSEECKKPGIANSLPSASPSQPLSALLHLLSMQNANQQCIGAKPGNMHANTSPRPITPLTPQGDGQSVLRIHNPQPQSTTPTLDPQQPASQAFPIMGDETTANLKAASSNTILNLSQPHVGTTTPDLSGSIISMINQMSSNSCLPTFAEKVCGSKMTEAYPEHSTYQINQPNHSPDVEDKGPVETIDSDTRLLAGCEPDHGLSLSTAPTSDLTNPATDPAISLPLAEAFPFMTQEQLLQLLSSNAGLPSLLPPFLGSLPLGLWTGSQPSTPGSNQSQHPPIGNQGSPLNLLNQAELPLNLLSLLNPAGSAAALPPVAGVETGEKPPGLQALLMASLLLGQNPAAMLPLPALNLELPTPPQQVFADGVSLEKPPALLDSVLMGPGLLEALQTLAPGADGQSLLLSAPLAAPPPAFLSLNPALLAAALAQTEPLPNHTPSPPPHSQGTLSSPALVSTSVSCGPLVSAGPEVCDPLAEQDKNSQTHHFLSPLLAPGVLGDLAALGNINSLHGLLGAGPLLLPQGVPLTQNQTTLNPLTCLQLTMAPALMGEKPVALHETPPPQDAAAPPHDSLSQQREAPGLFDPYGSFMDTIYTSFLQVSERGSDSNPLTFPALLQQASAPPSLSPRRACSVHNPDLSRLGPDVAQSPARGTPKPSGDSPPPPCRPAGAHALTVEEAKTHTSKHCVFSNGLRSEGGEEEEEEDEDEDAGVQEYLSPTQRTSRDEDEDISHAEQIRAEDVHTGSRRGRKRKQTLQMGSDLPGGIDSIIEEPSASAILVSRSSRSSRGKRRRVLR.
MO-AB-20807W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO20807W		100 µg	Inquiry
Protein Refseq: The length of the protein is 1003 amino acids long. The sequence is show below: MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLPDPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPAKNKRRKLAP.
MO-AB-58808W	Monoclonal	Marmoset	WB, ELISA	MO58808W		100 µg	Inquiry
Protein Refseq: The length of the protein is 1007 amino acids long. The sequence is show below: MNGGNESSRADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLPDPVPSGGSSSPCFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPATQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLLPPSTLQGRRPRAQAPSASHSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLAGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGDPFSGLGDLPPLLFPPLSAPPTLIALNSALLAASLDPPSGTTPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPGRGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKSIFSQVPPGVVRKSRRGRRRKYNPTRNSNSSRQDIMLEPSPTARVAVPLPPRARPGRPAKNKRRKLAP.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	A. thaliana (Arabidopsis thaliana), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
Clone	MO36276FC
Specificity	This antibody binds to Arabidopsis MBD6.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	The Arabidopsis genome is predicted to encode 13 canonical MBD proteins, although only three of them, MBD5, MBD6, and MBD7, specifically bind methylated CG sites in vitro. The functions of these plant MBD proteins are poorly understood, but available information is consistent with a conserved role as DNA methylation effectors leading to transcriptional repression.
Product Overview	Mouse Anti-Arabidopsis MBD6 Antibody is a mouse antibody against MBD6. It can be used for MBD6 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Methyl-CpG Binding Domain Protein 6; Methyl-CpG-Binding Protein MBD6; KIAA1887
UniProt ID	Q9LTJ1
Protein Refseq	The length of the protein is 225 amino acids long. The sequence is show below: MSDSVAGDFPPDPLLASGAFISSAGDGTLDSSAKRRPIQGGIGISGSGESVRIGMANGTDQVNHQTESKSRKRAAPGDNWLPPGWRVEDKIRTSGATAGSVDKYYYEPNTGRKFRSRTEVLYYLEHGTSKRGTKKAENTYFNPDHFEGQGSNRVTRTATVPPPPPPPLDFDFKNPPDKVSWSMANAGEEGWIPNIGDVKVQDSVRRDWSTAFTFITSRNPSKVSA.

Reference

Lang, Z., Lei, M., Wang, X., Tang, K., Miki, D., Zhang, H., ... & Zhu, J. K. (2015). The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing. Molecular cell, 57(6), 971-983.