Mouse Anti-Medaka IL-17A Antibody (MO-AB-00750R)
Cat: MO-AB-00750R
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Size: | |
Conjugate: | |
Inquiry |
- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Medaka (Oryzias latipes) |
Clone | MO00750R |
Specificity | This antibody binds to Medaka IL-17A. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Extracellular region or secreted |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | IL-17A (IL-17A, IL17A) is a potent pro-inflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8+ T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and resistance to bacteria and fungi. IL-17A acts on a wide range of cell types to induce the expression of cytokines, chemokines and metalloproteinases. Therefore, secretion of IL-17A promotes the inflammatory response, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased IL-17A expression is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It has also been linked to asthma, psoriasis, cancer and transplant rejection. |
Product Overview | This product is a mouse antibody against IL-17A. It can be used for IL-17A detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Interleukin-17A/F-2; IL-17A/F-2 |
UniProt ID | E3WEA8 |
Protein Refseq | The length of the protein is 142 amino acids long. The sequence is show below: MELPTHSICILMVICCSLRFSSCSDEGVLHPPDCNVTLQFSSEIFSLSRGNGNIHQRSMSPWRWRSTTVRHRIPSTLWEAECDSIFCSNPTSGQPKDYSLNSVPIYQNILVLNHVKGSHCYTASYHLVAVGCTCVWARSNQT. |
See other products for " IL-17A "
MO-AB-00749R | Mouse Anti-Medaka IL-17A Antibody (MO-AB-00749R) |
MOFAB-324W | Mouse Anti-IL-17A Antibody (MOFAB-324W) |
MOFAB-340W | Mouse Anti-IL-17A Antibody (MOFAB-340W) |
MO-AB-00751R | Mouse Anti-Medaka IL-17A Antibody (MO-AB-00751R) |
MOFAB-323W | Mouse Anti-IL-17A Antibody (MOFAB-323W) |
MOFAB-339W | Mouse Anti-IL-17A Antibody (MOFAB-339W) |
For Research Use Only | Not For Clinical Use.
Online Inquiry