Rabbit Anti-Mouse JNK1 / JNK2 / JNK3 Antibody (CBMOAB-00266FYA)
Cat: CBMOAB-00266FYA
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- Specifications
- Application Information
- Target
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Cattle (Bos taurus), Monkey (Macaca mulatta), Zebrafish (Danio rerio) |
| Clone | F00266FYA |
| Specificity | This antibody binds to Mouse JNK1 / JNK2 / JNK3 and has cross reactivity with Human, Rat, Cattle, Monkey, Zebrafish. |
| Format | Liquid or Lyophilized |
| Buffer | TBS, pH 7.4 |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Purified with Protein A affinity chromatography |
| Cellular Localization | Cytoplasm; Nucleus; Membrane; Mitochondrion |
Application Information
| Application | WB, IF, IP |
| Application Notes | WB: 1:1,000-1:5,000 ICC: 1:50-1:200 |
Target
| Introduction | The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Product Overview | Rabbit Anti-Mouse JNK1 / JNK2 / JNK3 (clone F00266FYA) Antibody (CBMOAB-00266FYA) is a Rabbit antibody against the JNK1 / JNK2 / JNK3. It can be used for JNK1 / JNK2 / JNK3 detection in Western Blot, Immunofluorescence, Immunoprecipitation. |
| Alternative Names | Mitogen-Activated Protein Kinase 8; Stress-Activated Protein Kinase 1c; C-Jun N-Terminal Kinase 1; JUN N-Terminal Kinase; MAP Kinase 8; EC 2.7.11.24; JNK-46; SAPK1c; PRKM8; SAPK1; JNK1 |
| Gene ID | 5599 |
| UniProt ID | P45983 |
For Research Use Only | Not For Clinical Use.
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