Rabbit Anti-Mouse TARDBP Antibody (CBMOAB-00304FYA)


Cat: CBMOAB-00304FYA
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio)
CloneF00304FYA
SpecificityThis antibody is binds to Mouse TARDBP and has cross reactivity with Human, Rat, Zebrafish.
FormatLiquid
BufferTBS, pH 7.4
PurificationPurified with Protein A affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, IP, IF, IHC, FC
Application NotesWB: 1:1,000-1:5,000
ICC: 1:100-1:500
IHC: 1:50-1:200
FC: 1:50-1:100
IP: 1:10-1:50

Target

IntroductionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Product OverviewRabbit Anti-Mouse TARDBP (clone F00304FYA) Antibody (CBMOAB-00304FYA) is a Rabbit antibody against the TARDBP. It can be used for TARDBP detection in Western Blot, Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Flow Cytometry.
Alternative NamesTAR DNA Binding Protein; TDP-43; TAR DNA-Binding Protein 43; TAR DNA-Binding Protein-43; ALS10; TDP43
Gene ID23435
UniProt IDQ13148
For Research Use Only | Not For Clinical Use.

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