Mouse Anti-MSH2 Antibody (CBMOAB-36731FYC)

Cat: CBMOAB-36731FYC

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Specifications
Application Information
Target
Reference

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-36731FYC	Monoclonal	A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Pig (Sus scrofa), Rhesus (Macaca mulatta), Tomato (Lycopersicon esculentum)	WB, ELISA	MO36731FC		100 µg	Inquiry
Protein Refseq: The length of the protein is 937 amino acids long. The sequence is show below: MEGNFEEQNKLPELKLDAKQAQGFLSFYKTLPNDTRAVRFFDRKDYYTAHGENSVFIAKTYYHTTTALRQLGSGSNALSSVSISRNMFETIARDLLLERNDHTVELYEGSGSNWRLVKTGSPGNIGSFEDVLFANNEMQDTPVVVSIFPSFHDGRCVIGMAYVDLTRRVLGLAEFLDDSRFTNLESSLIALGAKECIFPAESGKSNECKSLYDSLERCAVMITERKKHEFKGRDLDSDLKRLVKGNIEPVRDLVSGFDLATPALGALLSFSELLSNEDNYGNFTIRRYDIGGFMRLDSAAMRALNVMESKTDANKNFSLFGLMNRTCTAGMGKRLLHMWLKQPLVDLNEIKTRLDIVQCFVEEAGLRQDLRQHLKRISDVERLLRSLERRRGGLQHIIKLYQSTIRLPFIKTAMQQYTGEFASLISERYLKKLEALSDQDHLGKFIDLVECSVDLDQLENGEYMISSSYDTKLASLKDQKELLEQQIHELHKKTAIELDLQVDKALKLDKAAQFGHVFRITKKEEPKIRKKLTTQFIVLETRKDGVKFTNTKLKKLGDQYQSVVDDYRSCQKELVDRVVETVTSFSEVFEDLAGLLSEMDVLLSFADLAASCPTPYCRPEITSSDAGDIVLEGSRHPCVEAQDWVNFIPNDCRLMRGKSWFQIVTGPNMGGKSTFIRQVGVIVLMAQVGSFVPCDKASISIRDCIFARVGAGDCQLRGVSTFMQEMLETASILKGASDKSLIIIDELGRGTSTYDGFGLAWAICEHLVQVKRAPTLFATHFHELTALAQANSEVSGNTVGVANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSPSSMIINNEESGKRKSREDDPDEVSRGAERAHKFLKEFAAIPLDKMELKDSLQRVREMKDELEKDAADCHWLRQFL.
CBMOAB-51810FYA	Monoclonal	Rhesus (Macaca mulatta)	WB, ELISA	MO51810FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 434 amino acids long. The sequence is show below: MTWKRRCININNAARDLGLDPGKQIKLDSSTQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEITFIPNDIYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQGYDMEPAAKKCYLERENLRAIEPKDQCLILLTWKRKLCGGTRSACSQPERQNRCSSELS.
CBMOAB-06872HCB	Monoclonal	C. elegans (Caenorhabditis elegans)	WB, ELISA	MO06872HB		100 µg	Inquiry
Protein Refseq: The length of the protein is 849 amino acids long. The sequence is show below: MSGGKDEASDKALLKILKSKSPNTIAIFSRGEYFSVYGDDATFVATNIFKSDVCVKTFTLSTDNSQQMKYISVNRGQYEKVVRETIVLLRCSVELYSSEQGEWKMTKRGSPGNTVDFEQEIGVSDQAPILAIYIHPGDDDNRVTLCAWDAGNVRIVISEYIDTPSFSQTEQCIFGLCPTEYILVNEGSVAPKAKKIASMFTRMEVHNKQQLKPKSQWSDVIESVHLDYKDEAEKQNENIKECLQILHSNAADEYSISEKYSIFNYGTHGNMLIDSCAVEALELFQLNYNYLEKSNNLTLYNVLNKCKTLPGEKLLRDWLSRPLCQIDHINERLDIVEALFENQTIRQKLRDSILARMPDCSQLARRLMRKCTLQDLNRFYQAATLLETVEMQLIQLSEAEQFAPSINRLLKSEITEILKKVERFQVLCDEFFDFDYEKENKEIRVRVDFVPEIQEISEKLEQMERVAEKLRKKYSAKFECDNLKLDKNSQYGFYFRVTLKEEKSIRKKDVHILETTKGSGVKFSVGELSDINDEFLEFHLKYTRAEEEVISMLCKKAEEFIPLIPAMAQLIATLDVFVSLSTFAATSSGIYTRPNLLPLGSKRLELKQCRHPVIEGNSEKPFIPNDVVLDKCRLIILTGANMGGKSTYLRSAALSILLAQIGSFVPCSSATISVVDGIFTRVGASDKQSQGISTFMAEMLDCSAILQRATKNSFVVIDELGRGTSTFDGFGIASAIAQDILNRIQCLSIFATHFHEMGKLAEQPGAVALQMGVQIENNEIHMLYKVFEGVAQCSFGLQVAKMVGIDENVINKAAQLLEGLEKKLVIDSKKKKELLESADIRQAILSLVK.
MO-AB-14354W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO14354W		100 µg	Inquiry
Protein Refseq: The length of the protein is 934 amino acids long. The sequence is show below: MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAYKASPGNLSQFEDILFGNNDMSASIGVVGVKMSTVDGQRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITERKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGCQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQALEKHEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPAILEKGQGRIILKASRHACVEVQDEIAFIPNDVYFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQGYDIMEPAAKKCYLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT.
MO-AB-59420W	Monoclonal	Marmoset	WB, ELISA	MO59420W		100 µg	Inquiry
Protein Refseq: The length of the protein is 934 amino acids long. The sequence is show below: MAVQPKETLQLESAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTVHGEDALLAAREVFKTQGVIKYMGPAGAKNLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAFKASPGNLSQFEDILFGNNDTSASIGVVGVRMSTVDGQRQVGVGYVDSIQRKLGLCEFPDNDQFSNLEALLIQIGPKECVLPGGETAGDMGKLRQIIQRGGILITEKKKADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELTTFDFSQYMKLDIAAVRALNLFQGSVEDTTGSQSLAALLNKCKTPQGQRLVNQWIKQPLLDKNRIEERLNLVEAFVEDAELRQTLQEDLLRRFPDLNRLAKKFLRQAANLQDCYRLYQGINQLPNVIQALEKYEGKHQKLLLAVFVTPLTDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELREIMNDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPVILEKGQGRIILKASRHACVEVQDEVAFIPNDVYFEKNKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPKHVIECAKQKALELEEFQYIGESQGYDDMEPAAKRCFLEREQGEKIIQEFLSKVKQMPFTEMSEENITIKLKQLKAEVIAKNNSFVNEIISRIKVTT.
MO-AB-16094R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO16094R		100 µg	Inquiry
Protein Refseq: The length of the protein is 934 amino acids long. The sequence is show below: MAVQPKDTLQLDSAAEVGFVRFFQGMPEKPTTTVRLFDRGDFYTAHREDALLAAREVFKTQGVVKYMGPAGAKTLESVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKENDWYLAFKASPGNLSQFEDILFGNNDMSASIGVVGVKMSTVDGQRQVGVGYVDSTQRKLGLCEFPDNDQFSNLEALLIQIGPKECVMPGGETAGDMGKLRQVIQRGGILITERKRADFSTKDIYQDLNRLLKGKKGEQVNS.
MO-AB-27367R	Monoclonal	Pig (Sus scrofa)	WB, ELISA	MO27367R		100 µg	Inquiry
Protein Refseq: The length of the protein is 934 amino acids long. The sequence is show below: MAVQPKETLQLESAAEIGFVRFFQGMPEKPTTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVVKFMGPAGAKTLESVVLSKMNFESFVKDLLLVRQYRVEVYKNRAGNKASKEHDWYLAFKASPGNLSQFEDILFGNNDMSAPIGVVGVKMSTVDGQRQVGVGYVDSIQRKLGLCEFPDNDQLSNLEALLIQIGPKECVLPGGDTAGDMGKLRQVIQRGGILITERKRADFSTKDIYQDLNRLLKGKKGEQMNSAVLPEMENQVAVSSLSAVIKFLELLADDSNFGQFELTTFDFSQYMKLDMAAVRALNLFQGSVEDTAGSQSLAALLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLVEAFVEDAELRQSLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPNVIQAMEKYEGQHQALLLAVFVTPLIDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELREIMDDLEKKMQSTLISAARDLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSKLTSLNEEYTKNKTEYEEAQNAIVKEIVNISSGYVEPMQTLNDVLAQLDAVVSFAHVSNGAPVPYVRPVILEKGQGRITLKASRHACVEVQDEVAFIPNDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVVVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAIPEYIATKIGAFCMFATHFHELTALANQIPAVNNLHVAALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPRHVIECAKQKALELEEFQNIGAPQEHDEMEPAAKRCYLEREQGEKIIQEFVSKVKQVPFTEMSEENITMKLKQLKAEVMAKNNSFVNEIISRIKVTT.
MO-AB-05336H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO05336C		100 µg	Inquiry
Protein Refseq: The length of the protein is 676 amino acids long. The sequence is show below: LPEMEKQVAMSALAAVMKYLELLSDESNFGQFVMTNFDLSQYMKLDNAAVGALNLFPGSAEDTSGTQSLAGLLNKCKTPQGQRLVNQWIKQPLMDKNRVEERLNLVEAFVMDVELRQCLQEDLLRRFPDLNRLAKKFQRQTANLQDCYRLYQAVNHLPTVVQAIEKYEGTHQMLLLAVFATPLSDLSSDFSKFQEMIETTLDMDQVENHEFLVKASFDPNLTELREKMDELEKNMQGALGGAARELGLDAGKSIKLESNSQIGHYFRVTCKEEKALRNNKKFTTIDIQKNGVRFTNSKLSSLSEEYMRNREEYEEAQNAIVKEIITISAGYVDPIQTLNDVIAQLDAVVSFAHVSNSAPVPYVRPVILEKGQGRIVLHSARHPCIEMQDDVAFIPNDITFEKEKQMFQIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCDSAQVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATENSLIIIDELGRGTSTYDGFGLAWAISEYISTKIKAFCMFATHFHELTALADQVPTVNNLHVTALTTEDTLTMLYRIKKGVCDQSFGIHVAELANFPKHVIETAKEKALELEEFQYVGNPDDCDDEPARKRRCEEKEEGEKIIQDFLSRVKALPLTEMSEEEIKIKLKQFRADVLAKNNRFVSEVISRTKTGL.
MO-AB-34923H	Monoclonal	Tomato (Lycopersicon esculentum)	WB, ELISA	MO34923C		100 µg	Inquiry
Protein Refseq: The length of the protein is 943 amino acids long. The sequence is show below: MDENFEKQGKLPELKLDARQAQGFLSFFKTLPKDVRAVRLFDRRDYYTAHGDDATFIAKTYYHTTTALRQLGNGVGALSSVSVSRNMFETIARDILLERMDRTLELYEGSGSNWKLVKSGTPGNFGSFEDILFANNEMQDSPVIVALAPKFDQNGCTVGLGYVDITKRVLGLAEFLDDSHFTNLESALVALGCRECLVPTETGKSSESRPLYDAISRCGVMVTERKKTEFKGRDLVQDLGRLVKGSVEPVRDLVSSFECAAGALGCILSYAELLADDSNYGNYTVKQYNLDSYMRLDSAAMRALNVMESKSDANKNFSLFGLMNRTCTAGMGKRLLHMWLKQPLLDVDEINCRLDLVQAFVEDAALRQDLRQHLKRISDIERLTHNLERKRASLLHVVKLYQSGIRIPYIKSVLERYDGQFAPLIRERYIDSLEKWSDDNHLNKFIALVETAVDLDQLENGEYMISSAYDPNLSALKDEQETLEQQIHNLHKQTANDLDLPIDKSLKLDKGTQFGHVFRITKKEEPKVRRQLNSHYIVLETRKDGVKFTNTKLKKLGDRYQKILDEYKSCQKELVARVVQTVASFSEVFEGLAGSLSELDVLLSFADLASSCPTAYSRPNISPPDTGDIILEGCRHPCVEAQDWVNFIPNDCRLVRGESWFQIITGPNMGGKSTYIRQVGVNVLMAQVGSFVPCDNATISIRDCIFARVGAGDCQLKGVSTFMQEMLETASILKGATNRSLVIIDELGRGTSTYDGFGLAWAICEHIVEEIKAPTLFATHFHELTALANENGNNGHKQISSVANFHVSAHIDSSSRKLTMLYKVQPGACDQSFGIHVAEFANFPQSVVALAREKASELEDFSPRAMMPNDCKEVVSKRKREFDPHDVSRGTARARQFLQDFTQLPLDKMDLKQALQQLSQMKTDLEKNAVDSQWLQQFFSSSN.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Pig (Sus scrofa), Rhesus (Macaca mulatta), Tomato (Lycopersicon esculentum)
Clone	MO36731FC
Specificity	This antibody binds to Arabidopsis MSH2.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Plasma Membrane; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Product Overview	Mouse Anti-Arabidopsis MSH2 Antibody is a mouse antibody against MSH2. It can be used for MSH2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	MutS Homolog 2; HMSH2; MutS (E. Coli) Homolog 2 (Colon Cancer, Nonpolyposis Type 1); MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli); MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1; DNA Mismatch Repair Protein Msh2; MutS Protein Homolog 2
UniProt ID	O24617
Protein Refseq	The length of the protein is 937 amino acids long. The sequence is show below: MEGNFEEQNKLPELKLDAKQAQGFLSFYKTLPNDTRAVRFFDRKDYYTAHGENSVFIAKTYYHTTTALRQLGSGSNALSSVSISRNMFETIARDLLLERNDHTVELYEGSGSNWRLVKTGSPGNIGSFEDVLFANNEMQDTPVVVSIFPSFHDGRCVIGMAYVDLTRRVLGLAEFLDDSRFTNLESSLIALGAKECIFPAESGKSNECKSLYDSLERCAVMITERKKHEFKGRDLDSDLKRLVKGNIEPVRDLVSGFDLATPALGALLSFSELLSNEDNYGNFTIRRYDIGGFMRLDSAAMRALNVMESKTDANKNFSLFGLMNRTCTAGMGKRLLHMWLKQPLVDLNEIKTRLDIVQCFVEEAGLRQDLRQHLKRISDVERLLRSLERRRGGLQHIIKLYQSTIRLPFIKTAMQQYTGEFASLISERYLKKLEALSDQDHLGKFIDLVECSVDLDQLENGEYMISSSYDTKLASLKDQKELLEQQIHELHKKTAIELDLQVDKALKLDKAAQFGHVFRITKKEEPKIRKKLTTQFIVLETRKDGVKFTNTKLKKLGDQYQSVVDDYRSCQKELVDRVVETVTSFSEVFEDLAGLLSEMDVLLSFADLAASCPTPYCRPEITSSDAGDIVLEGSRHPCVEAQDWVNFIPNDCRLMRGKSWFQIVTGPNMGGKSTFIRQVGVIVLMAQVGSFVPCDKASISIRDCIFARVGAGDCQLRGVSTFMQEMLETASILKGASDKSLIIIDELGRGTSTYDGFGLAWAICEHLVQVKRAPTLFATHFHELTALAQANSEVSGNTVGVANFHVSAHIDTESRKLTMLYKVEPGACDQSFGIHVAEFANFPESVVALAREKAAELEDFSPSSMIINNEESGKRKSREDDPDEVSRGAERAHKFLKEFAAIPLDKMELKDSLQRVREMKDELEKDAADCHWLRQFL.

Reference

Reference

Molinier, J., Ramos, C., Fritsch, O., & Hohn, B. (2004). CENTRIN2 modulates homologous recombination and nucleotide excision repair in Arabidopsis. The Plant Cell, 16(6), 1633-1643.

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