Rabbit Anti-MyD88 (AA 200-270) Antibody (Cat MO-DKB-03141W)

Cat: MO-DKB-03141W
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Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus), Pig (Sus scrofa), Cattle (Bos taurus), Horse (Equus caballus), Guinea pig (Cavia porcllus), Primate, Sheep (Ovis aries), Frog (Xenopus), Zebrafish (Danio rerio)
SpecificityDue to the high sequence homology, this antibody is expected to detect multiple isotypes of MyD88 protein.
ImmunogenA synthetic peptide corresponding to human MyD88 (between amino acids 200-270).
EpitopeAA 200-270
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified
Cellular LocalizationCytoplasm

Application Information

ApplicationWB, IF, IHC, IHC-P
Application NotesWestern Blot: 0.5-2 ug/mL
Immunocytochemistry/Immunofluorescence: 1:100
Immunohistochemistry: 2-5 ug/mL
Immunohistochemistry-Paraffin: 2-5 ug/mL
The optimal dilution should be determined by the end user.


IntroductionThis gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Product OverviewThis product is a Rabbit antibody against the MyD88. It can be used for MyD88 detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesMyeloid differentiation primary response protein MyD88; myd8
UniProt IDB2GQ86
For Research Use Only | Not For Clinical Use.
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