Rabbit Anti-NPR1 (Center) Antibody (Cat MO-DKB-04072W)


Cat: MO-DKB-04072W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
SpecificityThis antibody is binds to A. thaliana NPR1.
ImmunogenA GST-fusion protein containing the middle region of arabidopsis thaliana NPR1 (AT1G64280).
EpitopeCenter
FormatLiquid or Lyophilized
BufferPBS, pH 7.4, 100 ug/mL BSA, 40% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified

Application Information

ApplicationWB
Application NotesWestern Blot: 1:500-1:2000
The optimal dilution should be determined by the end user.

Target

IntroductionGuanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2; MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).
Product OverviewThis product is a Rabbit antibody against the NPR1. It can be used for NPR1 detection in Western Blot.
Alternative NamesNatriuretic Peptide Receptor 1; Guanylate Cyclase A; Atrial Natriuretic Peptide Receptor Type A; Atrionatriuretic Peptide Receptor A; Natriuretic Peptide Receptor A; EC 4.6.1.2; ANPR-A; ANPRA; ANP-A; NPR-A; Regulatory protein NPR1; BTB/POZ domain-containing protein NPR1; Non-inducible immunity protein 1; Nim1; Nonexpresser of PR genes 1; Salicylic acid insensitive 1; Sai1; NIM1; SAI1; At1g64280; F15H21.6
UniProt IDP93002
For Research Use Only | Not For Clinical Use.
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