Mouse Anti-O. anatinus BAP1 Antibody (MO-AB-06330Y)
Cat: MO-AB-06330Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | O. anatinus (Ornithorhynchus anatinus) |
Clone | MO06330Y |
Specificity | This antibody binds to O. anatinus BAP1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Other locations; Cytosol; Nucleus |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. |
Product Overview | This product is a mouse antibody against BAP1. It can be used for BAP1 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Ubiquitin carboxyl-terminal hydrolase; EC 3.4.19.12; BAP1 |
UniProt ID | F6SMM8 |
Protein Refseq | The length of the protein is 680 amino acids long. The sequence is show below: MNKGWLELESDPGLFTLLVEDFGVRGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDDDIVNNMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRMKYESKLHVLKMNRQTVLEALQQLIRVTQPELIQTQKSQEAQAPEDPKPGSSKAPAVLDANRTHLASEGSHADGAEDTARPCQQAPTNSPPNKSKLAVKPPVSGHNGASANPSPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRQHQQYSDDEDDYEDEEEEDARNTNSALRQRVPLMVKAREXYLSHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCMRYNRAVRDLGPVISTGLLHLAEDGVLCPLIVTEGEKSSPTSSRQSELAQVVAKVEEKPLPEASDSKGTSRNAEQPGGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRHPR. |
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MO-AB-07965R | Mouse Anti-Cattle BAP1 Antibody (MO-AB-07965R) |
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For Research Use Only | Not For Clinical Use.
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