Mouse Anti-O. mykiss ABCG2 Antibody (MO-AB-10595Y)
Cat: MO-AB-10595Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | O. mykiss (Oncorhynchus mykiss) |
Clone | MO10595Y |
Specificity | This antibody binds to O. mykiss ABCG2. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Plasma membrane; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. |
Product Overview | This product is a mouse antibody against ABCG2. It can be used for ABCG2 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Breast cancer resistance protein; ABCG2 |
UniProt ID | A8IJF9 |
Protein Refseq | The length of the protein is 655 amino acids long. The sequence is show below: MSQPLNSQIPGMEDTKTNGTPKYESTGTAKSLQGSTVSFHNIHYKVTQRSGCLCIKRKTTTKDILIDLNGLMKPGLNAIMGATGSGKSSFLDVLAARKDPAGLAGEVLMDGAPQPPNFKCLSGYVVQDDVVLGTLTVRENFRFSAALRLPSSVSQKEKEDKVNRLITELGLTKVADSRVGTQLIRGISGGERKRTNIGMELIIDPPVLFLDEPTTGLDASTANSVLLLLKRMSSHGRTIILSIHQPRYSIFRLFDSLTLLVSGKQVYHGPAQSALDYFSNIGYTCEPHNNPADFFLDVINGDSTSIAFDRIKEADDSDPDRVTSSKQNIEDHLVQEYRGSQYLGETKAQLERITMTKEYGWKTPSRTIRYNTSFSTQFRWVLKRTFTNLILNPQTSFAQIGVTVFLALIVGAIFFGVKNDQSGLQNRMGALFFITTNQCFSSLSSAELFITERKLFIHEYISGYYRVSVYFLCKILSDIITLRTLPSIVFSCVAYFMIGYKATVEAFFLFMLTVALVAYTATAMTMAISADQSVVAIANIFMTIAFVFMMIFSGLLVNLPSIVEWLAWFQYLSIPRYGLTALQINEFVGLQFCGDIPLNGTLPPGMTCTGEDFLKNQGIDYTTWGLWQNHVALAIMTVIFLLIAYFKLRFIKKFT. |
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For Research Use Only | Not For Clinical Use.
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