Mouse Anti-O. mykiss BDNF Antibody (MO-AB-10732Y)
Cat: MO-AB-10732Y
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | O. mykiss (Oncorhynchus mykiss) |
| Clone | MO10732Y |
| Specificity | This antibody binds to O. mykiss BDNF. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Extracellular region or secreted |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer''s, Parkinson''s, and Huntington''s disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. |
| Product Overview | This product is a mouse antibody against BDNF. It can be used for BDNF detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | BDNF |
| UniProt ID | D0VPU4 |
| Protein Refseq | The length of the protein is 248 amino acids long. The sequence is show below: FSCMRAAPMRDAPGIRGHRTEGYLGAAVTAGQGHGTPQSGGGPGQHGGLPSLTDTFEQVIEELLEVEGEASQLGPGADKGQGGGGPSSVVTTETKDVDLYASRVMISNQVPLEPPLLFLLEEYKNYLDAANMSMRVRRHSDPSRRGELSVCDSISQWVTAVDKKTAIDMSGQTVTVLEKVPVPNGQLKQYFYETKCNPMGYTKEGCRGIDKRHYNSQCRTTQSYVRALTMDSKKKIGWRFIRIDTSCV. |
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For Research Use Only | Not For Clinical Use.
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