Rabbit Anti-PDK1 (AA 300-400) Antibody (Cat MO-DKB-03162W)
Cat: MO-DKB-03162W
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- Product Details
Specifications
Host species | Rabbit (Oryctolagus cuniculus) |
Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Cattle (Bos taurus), Chicken (Gallus gallus), Primate, Zebrafish (Danio rerio) |
Specificity | This antibody is binds to Human Pyruvate Dehydrogenase Kinase 1/PDK1 and has cross reactivity with Mouse, Mouse, Rat, Pig, Cattle, Chicken, Primate, Zebrafish Pyruvate Dehydrogenase Kinase 1/PDK1. |
Immunogen | A synthetic peptide used in the internal part of the human PDK1 protein sequence (between residues 300-400). |
Epitope | AA 300-400 |
Format | Liquid or Lyophilized |
Buffer | Tris-Glycine, 0.15M NaCl |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purification | Affinity purified |
Cellular Localization | Mitochondrion |
Application Information
Application | WB, IB |
Application Notes | Western Blot: 0.5-2 ug/mL The optimal dilution should be determined by the end user. |
Target
Introduction | Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. |
Product Overview | This product is a Rabbit antibody against the Pyruvate Dehydrogenase Kinase 1/PDK1. It can be used for Pyruvate Dehydrogenase Kinase 1/PDK1 detection in Western Blot, Immunoblotting. |
Alternative Names | pdk1; Pyruvate Dehydrogenase Kinase 1 |
UniProt ID | E7F3U3 |
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For Research Use Only | Not For Clinical Use.
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