Cat: MO-AB-23925R
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Pig (Sus scrofa) |
| Clone | MO23925R |
| Specificity | This antibody binds to Pig ATM. |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. |
| Product Overview | This product is a mouse antibody against ATM. It can be used for ATM detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Ataxia-telangiectasia mutated protein splice variant 1; Ataxia-telangiectasia mutated protein splice variant 2; Ataxia-telangiectasia mutated protein splice variant 6, Fragment; ATM |
| UniProt ID | A7IYP6 |
| Protein Refseq | The length of the protein is 245 amino acids long. The sequence is show below: MSLALNDLLICCRQLEHDRATERRKAVENFRHLIQDPETVQHLDQHSDSKQGKYLNWDAAFRFLQKYIQKETECLRTAKQNVSASTQATRQKKMQEISSLVKYFIKCANKRAPRLKCQELLNYIMDTVRDSSNNPIYGADYSNILLKDILSVRKYWCEISQQQWRELFLIYFTLYLKPSQDINRLLVARIIQAVTKGCCSQTDGLNSEFLDFFTKAIQNARQEKSSPGLNHILAAYVIFLKTLAA. |
See other products for " atm "
| MO-AB-01687H | Mouse Anti-Frog atm Antibody (MO-AB-01687H) |
| CBMOAB-66955FYA | Mouse Anti-Zebrafish atm Antibody (CBMOAB-66955FYA) |
| MO-AB-29073W | Mouse Anti-Dog ATM Antibody (MO-AB-29073W) |
| MO-AB-00211Y | Mouse Anti-Chicken ATM Antibody (MO-AB-00211Y) |
| CBMOAB-66953FYA | Mouse Anti-Zebrafish atm Antibody (CBMOAB-66953FYA) |
| CBMOAB-66954FYA | Mouse Anti-Zebrafish atm Antibody (CBMOAB-66954FYA) |
| CBMOAB-66952FYA | Mouse Anti-Zebrafish atm Antibody (CBMOAB-66952FYA) |
| MO-AB-23928R | Mouse Anti-Pig ATM Antibody (MO-AB-23928R) |
| MO-AB-23927R | Mouse Anti-Pig ATM Antibody (MO-AB-23927R) |
| CBMOAB-66957FYA | Mouse Anti-Zebrafish atm Antibody (CBMOAB-66957FYA) |
For Research Use Only | Not For Clinical Use.