Cat: MOFAB-085W
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- Product Details
Specifications
| Host species | Mouse |
| Clone | WQD11 |
| Specificity | These antibodies recognize quinidine. |
| Immunogen | Quinidine conjugated to KLH. |
| Format | Liquid |
| Buffer | PBS, pH 7.4 |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
| Purification | Protein G |
Application Information
| Application | ELISA |
| Application Notes | The optimal dilution should be determined by the end user. |
Target
| Introduction | Quinidine is a class I antiarrhythmic drug. Like all other class I antiarrhythmic drugs, quinidine acts primarily by blocking the fast inward sodium current (INa), which results in decreased phase 0 depolarization (decreased Vmax) of the cardiac action potential. Quinidine also blocks the slowly inactivated, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the fast (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI) , ATP-sensitive potassium channel (IKATP) and Ito. At micromolar concentrations, quinidine inhibits Na/K-ATPase by binding to the same receptor site as digitonin such as ouabain. |
| Product Overview | The Quinidine antibody is used as Drug antibodies. |
| Alternative Names | Quinidine; Quinidine |
Reference
See other products for " Quinidine "
For Research Use Only | Not For Clinical Use.