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Mouse Anti-Rabbit MYL2 Antibody (MO-AB-08909Y)


Cat: MO-AB-08909Y
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Lot Number

  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRabbit (Oryctolagus cuniculus)
CloneMO08909Y
SpecificityThis antibody binds to Rabbit MYL2.
FormatLyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Cytoskeleton

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionContractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
Product OverviewThis product is a mouse antibody against MYL2. It can be used for MYL2 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesMyosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2; MLC-2v; MYL2
UniProt IDQ7M2V4
Protein RefseqThe length of the protein is 165 amino acids long. The sequence is show below: MSPKKAKKRAEGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKDEIDQMFAAFPPDVTGNLDYKNLVHIITHGEEK.
For Research Use Only | Not For Clinical Use.

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