Cat: MO-AB-10416Y
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rabbit (Oryctolagus cuniculus) |
| Clone | MO10416Y |
| Specificity | This antibody binds to Rabbit USP14. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation. |
| Product Overview | This product is a mouse antibody against USP14. It can be used for USP14 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Ubiquitin carboxyl-terminal hydrolase 14; EC 3.4.19.12; Deubiquitinating enzyme 14; Ubiquitin thioesterase 14; Ubiquitin-specific-processing protease 14; USP14; TGT |
| UniProt ID | P40826 |
| Protein Refseq | The length of the protein is 493 amino acids long. The sequence is show below: MPLYSVTVKWGKEKFGGVELNTDEPPMVFKAQLFALTGVQPARQRVMVKGGTLKDDDWGNIKIKNGMTILMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATVQCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLHMAFPQFAEKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSAAAVAPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYLFTGLKLRLQEEITKQSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMVSFRSKFKDIEDKKVNQQPNASDKKSSPQKEVRYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSGHYVSWVKRKHDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVEIMEEENEQ. |
Reference
See other products for " USP14 "
| MO-AB-67488W | Mouse Anti-Marmoset USP14 Antibody (MO-AB-67488W) |
| MO-AB-23862H | Mouse Anti-Mallard USP14 Antibody (MO-AB-23862H) |
| MO-AB-21669W | Mouse Anti-Chimpanzee USP14 Antibody (MO-AB-21669W) |
| MO-AB-01612L | Mouse Anti-Elephant USP14 Antibody (MO-AB-01612L) |
| MO-AB-01611L | Mouse Anti-Elephant USP14 Antibody (MO-AB-01611L) |
| MO-AB-33977H | Mouse Anti-Nile tilapia usp14 Antibody (MO-AB-33977H) |
| MO-AB-08973H | Mouse Anti-Frog usp14 Antibody (MO-AB-08973H) |
| MO-AB-31138R | Mouse Anti-Pig USP14 Antibody (MO-AB-31138R) |
| MO-AB-22671R | Mouse Anti-Cattle USP14 Antibody (MO-AB-22671R) |
| MO-DKB-01179W | Rabbit Anti-USP14 Antibody (MO-DKB-01179W) |
For Research Use Only | Not For Clinical Use.