Cat: CBMOAB-34735FYA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta) |
| Clone | MO34735FYA |
| Specificity | This antibody binds to Rhesus A2M. |
| Format | Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Extracellular region or secreted |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. |
| Product Overview | Mouse Anti-Rhesus A2M (clone MO34735FYA) Antibody (CBMOAB-34735FYA) is a mouse antibody against A2M. It can be used for A2M detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | A2M |
| UniProt ID | F6TNV9 |
| Protein Refseq | The length of the protein is 1474 amino acids long. The sequence is show below: MGRNTLLHPSLVLLLLVLLPTDVSVSGKPQYMVLVPSLLHTETPEKGCVLLSYLNETVTVSASLESVRGNRSLFTDLEAENDVLHCVAFAVPKSSSNEEVMFLTVQVKGPTQEFKKRTTVMVKNEESLVFVQTDKSIYKPEQTVKFRVVSLDENFHPVNELIPLVYIQDPKGNRIAQWQSFQLEGGLKQLSFPLSSEPFQGSYKVVVQKKSGRRTEHPFTVEEFVLPKFEVQVTVPKIITILEEEMNVSVCGLYTYGKPVPGHVTVSICRKYSDASDCFGEDSKAFCEKFSGQLNSHGCFYQQVKTKVFQLKRKEYEMKLHTEAKIQEEGTVVELTGKKSSEITRTITKLSFVKVDSHFRQGIPFFGQVRLVDGKGVPIPNKVIFIRGNEANYYSNATTDEHGLVQFSINTTNVMGTTLTVRVKHKDRSPCYGYQWVSEEHEEAHHTAYLVFSPSKSFVHLEPLPHELPCGQTQTVQAHYILNGGALQGLKKLSFYYLIMARGGIVRTGTHGLLVKQEHMKGHFSISIPVKSDIAPVARLLIYAVLPTGDVIGDSAKYEVENCLDNKVDLSFRPSQSLPASHAHLQVTAAPQSLCALRAVDQSVLLMKPDAELSASSVYNLLPVKDLTGFPEPLNDQDDEDCVNRHNVYINGITYTPVSNTNEKDIYSFLQDMSLKAFTNSKIRKPKICPQLQQYEMHGPEGLRVGYYDSDVMGRGQARKLQLEEPHTETVRKYFPETWIWDLVVVNSSGVAEVGVTVPDTITDWKAGAFCLSQDSGLGISPTASLRAFQPFFVELTMPYSVIRGEAFTLKATVLNYLPKCIRVSVQLEASPAFLAVPVEKEQEPHCICANGRQTVSWAITPKSLGNVNFTVSAEALESQELCGTEVASVPQYGKKDTIIKPLLVEPEGLEKETTFNSLLCPSGGEVSEELSLKLPPNVVEESARASVSVLGDILGSAMQNIQNLLQMPYGCGEQNMVLFAPNIYVLDYLNETQQLTPEIESKAIGYLNTGYQRQLNYKHYDGSYSTFGERYGRNQGNTWLTAFVLKTFAQARAYIFIDEAHITQALIWLSQKQKDNGCFRSSGSLLNNAIKGGVEDEVTLSAYITIALLEIPLPVTHPVVRNALFCLESAWKTTQEGAHGSHVYTKALLAYAFALAGNQEKRKEVLESLNEEAVKKDNSVHWERPQKPKAPVGHFYEPQAPSAEVEMTSYVLLAYLTAQPAPTSEDLTSATNVVKWITKQQNSQGGFSSTQDTVVALHALSKYGAATFTRTGKAAQVTIQSSGTFSNKFQVDNSNRLLLQRVSLPELPGEYSMKVTGEGCVYLQTSLKYNILPEKEEFPFALGVQTLPATCEEPKAHTSFQISLSVSYTGSRSASNMAIVDVKMVSGFIPLKPTVKTLERSNHVSRTEVSNNHVLIYLDKVSNQTLSLFFTVLQDVPVRDLKPAVVKVYDYYETDEFAIAEYNAPCSKDLGNA. |
See other products for " A2M "
| MO-AB-06701R | Mouse Anti-Cattle A2M Antibody (MO-AB-06701R) |
| MO-AB-50149W | Mouse Anti-Marmoset A2M Antibody (MO-AB-50149W) |
| MO-AB-06700R | Mouse Anti-Cattle A2M Antibody (MO-AB-06700R) |
| MO-AB-06705R | Mouse Anti-Cattle A2M Antibody (MO-AB-06705R) |
| MO-AB-01108H | Mouse Anti-Frog a2m Antibody (MO-AB-01108H) |
| CBMOAB-34736FYA | Mouse Anti-Rhesus A2M Antibody (CBMOAB-34736FYA) |
| CBMOAB-34738FYA | Mouse Anti-Rhesus A2M Antibody (CBMOAB-34738FYA) |
| MO-AB-06710R | Mouse Anti-Cattle A2M Antibody (MO-AB-06710R) |
| MO-AB-06716R | Mouse Anti-Cattle A2M Antibody (MO-AB-06716R) |
| MO-AB-06718R | Mouse Anti-Cattle A2M Antibody (MO-AB-06718R) |
For Research Use Only | Not For Clinical Use.