Mouse Anti-Rhesus ABCC8 Antibody (CBMOAB-34831FYA)
Cat: CBMOAB-34831FYA
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta) |
| Clone | MO34831FYA |
| Specificity | This antibody binds to Rhesus ABCC8. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. |
| Product Overview | Mouse Anti-Rhesus ABCC8 Antibody is a mouse antibody against ABCC8. It can be used for ABCC8 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | ATP-binding cassette sub-family C member 8; ABCC8 |
| UniProt ID | H9FLV9 |
| Protein Refseq | The length of the protein is 251 amino acids long. The sequence is show below: EAFDAQVRKDVQGTQGARAIWQALSHAFGRRLVLSSTFRILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVSSQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMHLSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIF. |
See other products for " ABCC8 "
| CBMOAB-1305FYC | Mouse Anti-Arabidopsis ABCC8 Antibody (CBMOAB-1305FYC) |
| MO-AB-50203W | Mouse Anti-Marmoset ABCC8 Antibody (MO-AB-50203W) |
| MO-NAB-00040W | Mouse Anti-ABCC8 (AA 1548-1582, clone NW0157) Antibody (MO-NAB-00040W) |
| CBMOAB-64385FYA | Mouse Anti-Zebrafish abcc8 Antibody (CBMOAB-64385FYA) |
For Research Use Only | Not For Clinical Use.
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