Mouse Anti-Rhesus BARD1 Antibody (CBMOAB-36774FYA)


Cat: CBMOAB-36774FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO36774FYA
SpecificityThis antibody binds to Rhesus BARD1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a protein which interacts with the N-terminal region of BRCA1. In addition to its ability to bind BRCA1 in vivo and in vitro, it shares homology with the 2 most conserved regions of BRCA1: the N-terminal RING motif and the C-terminal BRCT domain. The RING motif is a cysteine-rich sequence found in a variety of proteins that regulate cell growth, including the products of tumor suppressor genes and dominant protooncogenes. This protein also contains 3 tandem ankyrin repeats. The BARD1/BRCA1 interaction is disrupted by tumorigenic amino acid substitutions in BRCA1, implying that the formation of a stable complex between these proteins may be an essential aspect of BRCA1 tumor suppression. This protein may be the target of oncogenic mutations in breast or ovarian cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product OverviewMouse Anti-Rhesus BARD1 Antibody is a mouse antibody against BARD1. It can be used for BARD1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesBARD1
UniProt IDF6U4Z0
Protein RefseqThe length of the protein is 777 amino acids long.
The sequence is show below: MPDNQQRRNRQPRVRSGNEPPSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDVKINRQLDSMIQLCSKLRNLLHDNKLSDLKEDDPRRSLFNDAENKKNSIKMWFSPRSKKVRYVVSKVSVRTQPEIKKDANGQQDSYEFVSTSPPADVSERAKKASARSRKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSWPLENNGKRGHHNRLSSPVSKRCRTSILSTSGDFVKQTMPSENTPLPECSSPPSCKRKVGGTSGRKKSNLSDEFISLSPGTPPSTLNSSSYRRVMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACSHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHMDIVKLLLSYGASRNAVNIFGLRPVDYTDDENMKSLLLLPEKNESSTTSHCSVMNIGQRRDGPLVLIGSGLSSEQQKMLSELAAILKAKKCTEFDSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRRVCEQEEKYEIPEGPHRSRLNREQLLPKLFDGCYFYLGGSFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYEDLSNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS.
See other products for " BARD1 "
MO-DKB-02312WRabbit Anti-BARD1 Antibody (MO-DKB-02312W)
MO-AB-21326WMouse Anti-Chimpanzee BARD1 Antibody (MO-AB-21326W)
CBMOAB-67436FYAMouse Anti-Zebrafish bard1 Antibody (CBMOAB-67436FYA)
CBMOAB-25066FYCMouse Anti-Arabidopsis BARD1 Antibody (CBMOAB-25066FYC)
MO-AB-01803HMouse Anti-Frog bard1 Antibody (MO-AB-01803H)
MO-AB-07968RMouse Anti-Cattle BARD1 Antibody (MO-AB-07968R)
For Research Use Only | Not For Clinical Use.
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