Rabbit Anti-S100B Antibody (C-terminal)
Cat: MO-NAB-00409W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Goat (Capra hircus), Zebrafish (Danio rerio) |
| Clone | NW0334 |
| Specificity | This antibody is binds to Human S100B and has cross reactivity with Mouse, Rat, Goat, Zebrafish. |
| Immunogen | C-terminal synthetic peptide in human S100B. |
| Epitope | The epitope is in the C-terminal of S100B. |
| Format | Liquid or Lyophilized |
| Buffer | TBS, pH7.4, 1% BSA, 40% Glycerol. |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Protein A purified |
| Cellular Localization | Cytoplasm; Nucleus |
Application Information
| Application | WB, IF, IHC, IHC-P, IP |
| Application Notes | Western Blot: 1:1000-1:5000 Immunofluorescence: 1:50-1:200 Immunohistochemistry-Paraffin: 1:50-1:200 |
Target
| Introduction | S100 calcium binding protein B (S100B) is a protein of the S-100 protein family.S100 protein is located in the cytoplasm and nucleus of a large number of cells and participates in the regulation of many cellular processes, such as cell cycle progression and differentiation. The S100 gene includes at least 13 members clustered on chromosome 1q21. However, the gene is located at 21q22.3.S100B is glial-specific and is mainly expressed by astrocytes, but not all astrocytes express S100B. It has been shown that S100B is expressed only by mature astrocyte subtypes that surround blood vessels and cells expressing NG2. The protein may play a role in neurite outgrowth, melanoma cell proliferation, Ca2+ flux stimulation, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing central nervous system, it acts as a neurotrophic factor and neuronal survival protein. In adult organisms, it is usually elevated due to damage to the nervous system, which makes it a potential clinical marker. |
| Product Overview | This product is a Rabbit antibody against the C-terminal of the S100B. It can be used for S100B detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation. |
| Alternative Names | S100B; NEF; S100; S100-B; S100beta; S100 calcium binding protein B |
| Gene ID | 6285(Human); 20203(Mouse); 25742(Rat) |
| UniProt ID | P04271(Human); P50114(Mouse); P04631(Rat) |
See other products for " S100B "
| MOFY-0622-FY172 | Rabbit Anti-S100B Antibody (MOFY-0622-FY172) |
| MO-AB-38142W | Mouse Anti-Goat S100B Antibody (MO-AB-38142W) |
| MO-AB-28799H | Mouse Anti-Rat S100b Antibody (MO-AB-28799H) |
| MO-AB-63755W | Mouse Anti-Marmoset S100B Antibody (MO-AB-63755W) |
| MO-AB-17554Y | Mouse Anti-Sheep S100B Antibody (MO-AB-17554Y) |
| MOFY-1222-FY100 | Rabbit Anti-S100B Antibody (MOFY-1222-FY100) |
| MO-AB-23530W | Mouse Anti-Chimpanzee S100B Antibody (MO-AB-23530W) |
| MO-AB-33221W | Mouse Anti-Dog S100B Antibody (MO-AB-33221W) |
| MO-AB-19699R | Mouse Anti-Cattle S100B Antibody (MO-AB-19699R) |
| CBMOAB-00281FYA | Rabbit Anti-Mouse S100B Antibody (CBMOAB-00281FYA) |
For Research Use Only | Not For Clinical Use.
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