Mouse Anti-S2 Antibody
Cat: MO-NAB-00877W
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- Product List
- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | SARS-CoV-2 (2019-nCoV) |
| Clone | NW0800 |
| Specificity | Recognize SARS-CoV-2 S2 protein |
| Immunogen | Recombinant SARS-CoV-2 S2 protein |
| Format | Liquid or Lyophilized |
| Buffer | PBS, pH7.4, 50% glycerol |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Application Information
| Application | WB, ELISA |
| Application Notes | Elisa: 1:4000-1:8000 WB: 1:1000-5000 |
Target
| Introduction | Coronavirus disease 2019 is a newly emerging infectious disease that is currently spreading globally. It is caused by a new type of coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2 plays a key role in the process of receptor recognition and cell membrane fusion, and is composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain that recognizes and binds to the host receptor angiotensin converting enzyme 2, while the S2 subunit mediates viral cell membrane fusion by forming a six-helix bundle through two heptapeptide repeat domains. In this review, we focused on the latest research progress in the structure, function and development of antiviral drugs targeting S protein. |
| Product Overview | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant SARS-CoV-2(2019-nCoV) S2 protein. |
| Alternative Names | S glycoprotein; E2; Peplomer protein; Spike protein S2; S |
| UniProt ID | P0DTC2 |
For Research Use Only | Not For Clinical Use.
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