Mouse Anti-Sea-anemone WNT3 Antibody (MO-AB-14042Y)


Cat: MO-AB-14042Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivitySea-anemone
CloneMO14042Y
SpecificityThis antibody binds to Sea-anemone WNT3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationExtracellular region or secreted

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Product OverviewThis product is a mouse antibody against WNT3. It can be used for WNT3 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein Wnt; WNT3
UniProt IDQ19R74
Protein RefseqThe length of the protein is 342 amino acids long. The sequence is show below: MRVIITAIVPLISLLVSSEAVWWTLGTQLSVSSDPAKKSMLCYVTRQFNSRQQEVCRKNPDLMEHVAHGAKYGVHECRHQFRNRRWNCSTIRESGSLFESVLSKGCREAAFVHAVTAAGVAHSVTDACSKGRIESCDCDRNLSGRSSKGWTWSGCNSNIKFGVWFSKQFTEARERGDDLRQIMNRHNSRAGRKALEELVWRKYKCHGLSGSCSMKTCWMQQANFRQIGDHLKVKYDSAVEMTTKVNRRGKKRLKPKYSHFKKPSDKDLIYFETSPNYCDKNVTVGSLGTSGRQCNYTSNGIDGCELLCCGRGHNIQQAKITRNCNCVFKWCCEVKCERCKEV.
For Research Use Only | Not For Clinical Use.
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