Mouse Anti-Sheep CD14 Antibody (MO-AB-14487Y)
Cat: MO-AB-14487Y
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Sheep (Ovis aries) |
| Clone | MO14487Y |
| Specificity | This antibody binds to Sheep CD14. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma membrane |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL) and mediates the cytokine release induced by LDL. |
| Product Overview | This product is a mouse antibody against CD14. It can be used for CD14 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14 |
| UniProt ID | Q06AV9 |
| Protein Refseq | The length of the protein is 373 amino acids long. The sequence is show below: MVCVPYLLLLLLPPLLRVSADTTEPCELDDDDFRCVCNFTDPKPDWSSAVQCMVAVEVEIRGGGHSLDQFLKGVNTDPKQYADTIKALRVRRLKLGAAQVPAQLLVAVLRALGYSRLKELTLEDLEVTGPTPPTPLEATGPALTTLSLRNVSWATGGAWLGELQQWLKPGLRALNIAQAHSLAFPCAGLSTFEALTTLDLSDNPSLGDSGLMAALCPNKFPALQYLALRNAGMETPSGVCAALAAARVQPQSLDLSHNSLRVTAPGATRCVWPSALSSLNLSFAGLEQVPKGLPTKLSVLDLSCNKLSREPRREELPEVNVLTLDGNPFLDPGALKHQDDPMISGVVPACARSALTMGVSGTLALLQGARGFA. |
See other products for " CD14 "
| MOFY-0522-FY64 | Mouse Anti-CD14 Antibody (MOFY-0522-FY64) |
| MO-AB-01043Y | Mouse Anti-Chicken Cd14 Antibody (MO-AB-01043Y) |
| CBMOAB-00021FYA | Mouse Anti-Cattle CD14 Antibody (CBMOAB-00021FYA) |
| MO-AB-24426R | Mouse Anti-Pig CD14 Antibody (MO-AB-24426R) |
| CBMOAB-00023FYA | Mouse Anti-Cattle CD14 Antibody (CBMOAB-00023FYA) |
| MO-AB-07515Y | Mouse Anti-Rabbit CD14 Antibody (MO-AB-07515Y) |
| CBMOAB-38622FYA | Mouse Anti-Rhesus CD14 Antibody (CBMOAB-38622FYA) |
| MO-AB-52526W | Mouse Anti-Marmoset CD14 Antibody (MO-AB-52526W) |
| CBMOAB-00020FYA | Mouse Anti-Cattle CD14 Antibody (CBMOAB-00020FYA) |
| MO-AB-09769R | Mouse Anti-Cattle CD14 Antibody (MO-AB-09769R) |
For Research Use Only | Not For Clinical Use.
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