Mouse Anti-smad1 Antibody (CBMOAB-06378FYB)


Cat: CBMOAB-06378FYB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-06378FYB Monoclonal Zebrafish (Danio rerio), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Medaka (Oryzias latipes), O. anatinus (Ornithorhynchus anatinus), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Zebrafish WB, ELISA MO06378FYB 100 µg
MO-AB-01411L Monoclonal Elephant (Loxodonta africana) WB, ELISA MO01411L 100 µg
MO-AB-01612R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO01612R 100 µg
MO-AB-04056Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO04056Y 100 µg
MO-AB-06895Y Monoclonal O. anatinus (Ornithorhynchus anatinus) WB, ELISA MO06895Y 100 µg
MO-AB-07807H Monoclonal Frog (Xenopus laevis) WB, ELISA MO07807C 100 µg
MO-AB-08830W Monoclonal Cat (Felis catus) WB, ELISA MO08830W 100 µg
MO-AB-10030Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO10030Y 100 µg
MO-AB-17713Y Monoclonal Sheep (Ovis aries) WB, ELISA MO17713Y 100 µg
MO-AB-20543R Monoclonal Cattle (Bos taurus) WB, ELISA MO20543R 100 µg
MO-AB-21205W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO21205W 100 µg
MO-AB-23743H Monoclonal Mallard (Anas platyrhynchos) WB, ELISA MO23743C 100 µg
MO-AB-33439W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO33439W 100 µg
MO-AB-35715W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO35715W 100 µg
MO-AB-42598W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO42598W 100 µg
MO-AB-46597W Monoclonal Horse (Equus caballus) WB, ELISA MO46597W 100 µg
MO-AB-64844W Monoclonal Marmoset WB, ELISA MO64844W 100 µg
MOFY-1222-FY52 Polyclonal Zebrafish WB, IHC, ICC, IF, ELISA 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Medaka (Oryzias latipes), O. anatinus (Ornithorhynchus anatinus), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Zebrafish
CloneMO06378FYB
SpecificityThis antibody binds to Zebrafish smad1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.
Product OverviewMouse Anti-Zebrafish smad1 Antibody is a mouse antibody against smad1. It can be used for smad1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMothers against decapentaplegic homolog; MAD homolog; Mothers against DPP homolog; SMAD family member; smad
UniProt IDQ7T082
Protein RefseqThe length of the protein is 473 amino acids long.
The sequence is show below: MNVTSLFSFTSPAVKRLLGWKQGDEEEKWAEKAVDALVKKLKKKKGAMEELERALSCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALECCEFPFGSKQKDVCINPYHYKRVDSPVLPPVLVPRNSEFNAKLSMLPRFRNPLHQTEPPMPQNATFPDSFPQQPANALPFTPNSPTNSYPSSPNSGTGSTATFPHSPSSSDPGSPFQMPETPPPAYMPPEEPMTQDCPQPMDTNLLAPNLPLEISNRTDVHPVAYQEPKHWCSIVYYELNNRVGEAFLASSTSVLVDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSRCSLKIFNNQEFAELLAQSVNHGFEAVYELTKMCTIRMSFVKGWGAKYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS.
For Research Use Only | Not For Clinical Use.
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