Mouse Anti-smc1a Antibody (CBMOAB-06465FYB)


Cat: CBMOAB-06465FYB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-06465FYB Monoclonal Zebrafish (Danio rerio), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Guinea pig (Cavia porcellus), Marmoset, Medaka (Oryzias latipes), Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries) WB, ELISA MO06465FYB 100 µg
CBMOAB-58505FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO58505FYA 100 µg
MO-AB-01424L Monoclonal Elephant (Loxodonta africana) WB, ELISA MO01424L 100 µg
MO-AB-01621R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO01621R 100 µg
MO-AB-17645W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO17645W 100 µg
MO-AB-17725Y Monoclonal Sheep (Ovis aries) WB, ELISA MO17725Y 100 µg
MO-AB-20573R Monoclonal Cattle (Bos taurus) WB, ELISA MO20573R 100 µg
MO-AB-30247R Monoclonal Pig (Sus scrofa) WB, ELISA MO30247R 100 µg
MO-AB-33450W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO33450W 100 µg
MO-AB-33799H Monoclonal Nile tilapia (Oreochromis niloticus) WB, ELISA MO33799C 100 µg
MO-AB-35722W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO35722W 100 µg
MO-AB-42606W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO42606W 100 µg
MO-AB-64896W Monoclonal Marmoset WB, ELISA MO64896W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Guinea pig (Cavia porcellus), Marmoset, Medaka (Oryzias latipes), Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rhesus (Macaca mulatta), Sheep (Ovis aries)
CloneMO06465FYB
SpecificityThis antibody binds to Zebrafish smc1a.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionProper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product OverviewMouse Anti-Zebrafish smc1a Antibody is a mouse antibody against smc1a. It can be used for smc1a detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesStructural maintenance of chromosomes protein; smc1
UniProt IDE7F0X6
Protein RefseqThe length of the protein is 1232 amino acids long.
The sequence is show below: MGYLKLIEIENFKSYKGRQIIGPFHKFTAIIGPNGSGKSNLMDAISFVLAEKTSNLRVKTLKDLIHGAPVGKPAANRAFVSMVYCEDNGEECTFTRAIIGSSSEYRINSKVVGLSDYSEELEKLGILIKARNFLVFQGAVESIAMKNPKERTALFEEISRSGELAQEYDRRKKEMVKAEEDTQFSYHRKKNIAAERKEAKQEKEEAERYQRLKDEVVRAHVQLQLFKLYHNEEEIEKLNRELSQRNREIDKDRKKMDHVEEELKDKKKELGRMMRDQQNVEKEIKEKDAELNQKRPQYIKAKENTAHKIKKLEVARKSLQNAQKMYKKRKADIEELDREQGAVEMSRQEFEERMEEEAQSQGQDLTLEENQVKQYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKIETEAKIKQKIREIEENQKRIEKLEDYIATSRQSLDEQRRMEEELTEEVELAKRRIDEINMELNQVMEQLGDARIDRQENSRQQRKAEIMESIKRLYPGSVYGRLIDLCQPTQKKYQIAVTKVLGKNMDAIIVDSEKTGRDCIQYIKEQRGEPETFLPLDYLEVKPTDEKLRELRGAKLVIDVIRYEPPHIKKALQYACGNALVCENVEDARRIAFGGPYRHKTVALDGTLFQKSGVISGGASDLKAKARRWDEKAVDKLKEKKEKLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLSLNMQEKSKLESELANFGPRINDIKRIIQSRERDITQLRDRMNLVEDEVFFEFCKEIGVRNIREFEEEKVKRQNEIAKKRLEFETQKTRLAIQLDYEKNQLKEDQEKVMMWEQTVKKDENEIERLKKEEHRHMKIIDETMAQLQDLKNQHLTKKGEVNDKNREMEEIRKKLGSANKELTQLQKEVTAIETKLEQKRSDRHNLLQACKMQDIKLPLKSGTMDDISQGEGGSQVEDAISSPKASSSVHAKEALIEIDYSNLNEDLKDALSEDEIKGEMNTLQQRLNEQQSILQRISAPNMKAMEKLESVRDKFQETSDEFEAARKRAKKAKQAFEQIKKERFDRFNACFESVATNIDEIYKALSRNSSAQAFLGPENPEEPYLDGINYNCVAPGKRFRPMDNLSGGEKTVAALALLFAIHSYKPAPFFVLDEIDAALDNTNIGKVANYIKDQSVQNFQAIVISLKEEFYTKADSLIGVYPEQGDCVISKVLTFDLSQYPDANPNPND.
For Research Use Only | Not For Clinical Use.
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