Mouse Anti-tab1 Antibody (CBMOAB-08482FYB)
Cat: CBMOAB-08482FYB
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
CBMOAB-08482FYB | Monoclonal | Zebrafish (Danio rerio), C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Chicken (Gallus gallus), Rhesus (Macaca mulatta), Marmoset | WB, ELISA | MO08482FYB | 100 µg | ||
CBMOAB-11864HCB | Monoclonal | C. elegans (Caenorhabditis elegans) | WB, ELISA | MO11864HB | 100 µg | ||
CBMOAB-59641FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO59641FYA | 100 µg | ||
MO-AB-08235H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO08235C | 100 µg | ||
MO-AB-10983W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO10983W | 100 µg | ||
MO-AB-65778W | Monoclonal | Marmoset | WB, ELISA | MO65778W | 100 µg | ||
MO-DKB-01303W | Polyclonal | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Chicken (Gallus gallus), Rhesus (Macaca mulatta) | WB, IF | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Zebrafish (Danio rerio), C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Chicken (Gallus gallus), Rhesus (Macaca mulatta), Marmoset |
Clone | MO08482FYB |
Specificity | This antibody binds to Zebrafish tab1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus; Cytosol |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported. |
Product Overview | Mouse Anti-Zebrafish tab1 Antibody is a mouse antibody against tab1. It can be used for tab1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Map3k7ip1 protein; tab1; map3k7ip |
UniProt ID | Q6NUU7 |
Protein Refseq | The length of the protein is 498 amino acids long. The sequence is show below: AAQRRSLMQSNQSWTDDLPLCQLCGVGSSPNCVYGPDGKGTQSHPNEDGHFRFSTESCFLYGVFNGFEGSRVASFVCQCLTAELLLGQLSSGDTDADVRRILTQAFDVVEKSYFETIDDALAEKANLQTQLPEGAYVSAQTQKIADRLKTLEQEVSGGATAIVALILNNKLYIANVGTNRALLCKTTSDGQNQVIQIGRAHTTDNEDELTRLAQLGLDPVRLRQTAVISGQSSTRRIGDYKVKFNYTDIDVLSAAKHKPIIAEPEIHGGQSLAGVTGFLLLMSEGLIKALEAAHGPEQVNQEVVAMVAAELAQQGSLEAAAQAVVERVKRLHHDVFVSGRQRAQHCAHHEDMTLLIRVINYTLADGSLTPTQGGRIYPVSVPYSNHQSTSKTSVTLSLVMPAQGTLTNGSSTSSTLEGDTPTAGNQSPSTTLQSTNTHTQSSSSSSGDGSLFRQRSNQAAQPDETGRVPPYVDFTQFFRLWGKDHNDSQTVSAELGPQ. |
For Research Use Only | Not For Clinical Use.
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