Mouse Anti-tab1 Antibody (CBMOAB-08482FYB)


Cat: CBMOAB-08482FYB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-08482FYB Monoclonal Zebrafish (Danio rerio), C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Chicken (Gallus gallus), Rhesus (Macaca mulatta), Marmoset WB, ELISA MO08482FYB 100 µg
CBMOAB-11864HCB Monoclonal C. elegans (Caenorhabditis elegans) WB, ELISA MO11864HB 100 µg
CBMOAB-59641FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO59641FYA 100 µg
MO-AB-08235H Monoclonal Frog (Xenopus laevis) WB, ELISA MO08235C 100 µg
MO-AB-10983W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO10983W 100 µg
MO-AB-65778W Monoclonal Marmoset WB, ELISA MO65778W 100 µg
MO-DKB-01303W Polyclonal Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Chicken (Gallus gallus), Rhesus (Macaca mulatta) WB, IF 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), C. elegans (Caenorhabditis elegans), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Chicken (Gallus gallus), Rhesus (Macaca mulatta), Marmoset
CloneMO08482FYB
SpecificityThis antibody binds to Zebrafish tab1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Product OverviewMouse Anti-Zebrafish tab1 Antibody is a mouse antibody against tab1. It can be used for tab1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMap3k7ip1 protein; tab1; map3k7ip
UniProt IDQ6NUU7
Protein RefseqThe length of the protein is 498 amino acids long.
The sequence is show below: AAQRRSLMQSNQSWTDDLPLCQLCGVGSSPNCVYGPDGKGTQSHPNEDGHFRFSTESCFLYGVFNGFEGSRVASFVCQCLTAELLLGQLSSGDTDADVRRILTQAFDVVEKSYFETIDDALAEKANLQTQLPEGAYVSAQTQKIADRLKTLEQEVSGGATAIVALILNNKLYIANVGTNRALLCKTTSDGQNQVIQIGRAHTTDNEDELTRLAQLGLDPVRLRQTAVISGQSSTRRIGDYKVKFNYTDIDVLSAAKHKPIIAEPEIHGGQSLAGVTGFLLLMSEGLIKALEAAHGPEQVNQEVVAMVAAELAQQGSLEAAAQAVVERVKRLHHDVFVSGRQRAQHCAHHEDMTLLIRVINYTLADGSLTPTQGGRIYPVSVPYSNHQSTSKTSVTLSLVMPAQGTLTNGSSTSSTLEGDTPTAGNQSPSTTLQSTNTHTQSSSSSSGDGSLFRQRSNQAAQPDETGRVPPYVDFTQFFRLWGKDHNDSQTVSAELGPQ.
For Research Use Only | Not For Clinical Use.
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