Rabbit Anti-TARDBP Antibody (MO-DKB-00316W)


Cat: MO-DKB-00316W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Human TARDBP and has cross reactivity with Mouse, Rat, Zebrafish.
ImmunogenHuman TARDBP
FormatLiquid or Lyophilized
BufferPBS pH 7.3, 50% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAntigen Affinity Purified

Application Information

ApplicationELISA, WB, IHC, IF, IP

Target

IntroductionHIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Product OverviewThis product is a rabbit antibody against the TARDBP. It can be used for TARDBP detection in Enzyme-Linked Immunosorbent Assay, Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation.
Alternative NamesTAR DNA Binding Protein; TDP-43; TAR DNA-Binding Protein 43; TAR DNA-Binding Protein-43; ALS10; TDP43
UniProt IDQ13148
For Research Use Only | Not For Clinical Use.
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