Rabbit Anti-USP14 Antibody


Cat: MO-NAB-00405W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Zebrafish (Danio rerio)
CloneNW0330
SpecificityThis antibody is binds to Human USP14 and has cross reactivity with Zebrafish.
FormatLiquid or Lyophilized
BufferTBS, pH7.4, 1% BSA, 40% Glycerol.
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein A purified
Cellular LocalizationCytoplasm; Cell membrane

Application Information

ApplicationWB, FC, IF, IHC, IHC-P
Application NotesWestern Blot: 1:500-1:2000
Flow Cytometry: 1:50-1:100
Immunofluorescence: 1:50-1:200
Immunohistochemistry-Paraffin: 1:50-1:200

Target

IntroductionThis gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Product OverviewThis product is a Rabbit antibody against the USP14. It can be used for USP14 detection in Western Blot, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesUbiquitin Specific Peptidase 14; Ubiquitin Specific Peptidase 14 (TRNA-Guanine Transglycosylase); Ubiquitin Specific Protease 14 (TRNA-Guanine Transglycosylase); Deubiquitinating Enzyme 14; Ubiquitin Thioesterase 14; TGT; TRNA-Guanine Transglycosylase, 60-KD Subunit
Gene ID9097(Human); 59025(Mouse); 291796(Rat)
UniProt IDP54578(Human); Q9JMA1(Mouse)
For Research Use Only | Not For Clinical Use.
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