Mouse Anti-Yeast AHP1 Antibody (CBMOAB-00162CR)


Cat: CBMOAB-00162CR
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast
CloneMO00162CR
SpecificityThis antibody binds to Yeast AHP1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPeroxisome; Cytosol; Other locations; Plasma Membrane; Mitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Preferentially eliminates organic peroxides rather than hydrogen peroxide (PubMed:10391912, PubMed:9988687, PubMed:10681558). Relays alkyl hydroperoxides as a signal to the transcription factor CAD1/YAP2 by inducing the formation of intramolecular disulfide bonds in CAD1, which causes its nuclear accumulation and activation (PubMed:20145245). Involved in cellular Mn homeostasis (PubMed:10635552).
Product OverviewMouse Anti-Yeast AHP1 Antibody is a mouse antibody against AHP1. It can be used for AHP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPeroxiredoxin type-2; EC 1.11.1.15; AHPC1; Cytoplasmic thiol peroxidase 3; cTPx 3; Peroxiredoxin type II; Peroxisomal alkyl hydroperoxide reductase; TPx type II; Thiol-specific antioxidant II; TSA II; Thioredoxin peroxidase type II; Thioredoxin reductase; AHP1; YLR109W
UniProt IDP38013
Protein RefseqThe length of the protein is 176 amino acids long. The sequence is show below: MSDLVNKKFPAGDYKFQYIAISQSDADSESCKMPQTVEWSKLISENKKVIITGAPAAFSPTCTVSHIPGYINYLDELVKEKEVDQVIVVTVDNPFANQAWAKSLGVKDTTHIKFASDPGCAFTKSIGFELAVGDGVYWSGRWAMVVENGIVTYAAKETNPGTDVTVSSVESVLAHL.
For Research Use Only | Not For Clinical Use.
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