Mouse Anti-Yeast NR3C1 Antibody (MO-NAB-00236W)
Cat: MO-NAB-00236W
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Guinea Pig (Cavia porcellus), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Yeast |
Clone | NW0103 |
Immunogen | Partially purified rat GR. |
Format | Liquid or Lyophilized |
Buffer | PBS, pH 7.2 |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | Protein G purified |
Application Information
Application | WB, ChIP, FC, GS, IF, IHC, IHC-P, IP, Neut |
Application Notes | WB: 5 ug/mL ChIP: 1/10-1/500 FC: 1/10-1/1000 GS: 1/10-1/100 IF: 1/10-1/500 IHC: 1/10-1/500 IHC-P: 5 ug/mL IP: 1/10-1/500 |
Target
Introduction | This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011] |
Product Overview | Mouse Anti-Yeast NR3C1 (clone NW0103) Antibody (MO-NAB-00236W) is a Mouse antibody against the epitope of the GR/NR3C1. It can be used for GR/NR3C1 detection in Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Gel Super Shift Assay, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Neutralization Assay. |
Alternative Names | Nuclear Receptor Subfamily 3 Group C Member 1; Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor); Glucocorticoid Receptor; GRL; GR; Nuclear Receptor Subfamily 3, Group C, Member 1 |
Gene ID | 2908 |
UniProt ID | P04150 |
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For Research Use Only | Not For Clinical Use.
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