Mouse Anti-Yeast NR3C1 Antibody (MO-NAB-00236W)


Cat: MO-NAB-00236W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Guinea Pig (Cavia porcellus), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries), Yeast
CloneNW0103
ImmunogenPartially purified rat GR.
FormatLyophilized
BufferPBS, pH 7.2
StorageStore at -20°C. Avoid freeze-thaw cycles.
PurityProtein G purified

Application Information

ApplicationWB, ChIP, FC, GS, IF, IHC, IHC-P, IP, Neut
Application NotesWB: 5 ug/mL
ChIP: 1/10-1/500
FC: 1/10-1/1000
GS: 1/10-1/100
IF: 1/10-1/500
IHC: 1/10-1/500
IHC-P: 5 ug/mL
IP: 1/10-1/500

Target

IntroductionThis gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]
Product OverviewMouse Anti-Yeast NR3C1 (clone NW0103) Antibody (MO-NAB-00236W) is a Mouse antibody against the epitope of the GR/NR3C1. It can be used for GR/NR3C1 detection in Western Blot, Chromatin Immunoprecipitation, Flow Cytometry, Gel Super Shift Assay, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Neutralization Assay.
Alternative NamesNuclear Receptor Subfamily 3 Group C Member 1; Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor); Glucocorticoid Receptor; GRL; GR; Nuclear Receptor Subfamily 3, Group C, Member 1
Gene ID2908
UniProt IDP04150
For Research Use Only | Not For Clinical Use.

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