Cat: CBMOAB-00056CR
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Yeast |
| Clone | MO00056CR |
| Specificity | This antibody binds to Yeast PPH3. |
| Format | Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Forms the histone H2A phosphatase complex in association with the regulatory subunits PSY2 and PSY4, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint. PPH3 is directly involved in the dephosphorylation and activation of the transcription factor GLN3 in response to nutrient availability. |
| Product Overview | Mouse Anti-Yeast PPH3 (clone MO00056CR) Antibody (CBMOAB-00056CR) is a mouse antibody against PPH3. It can be used for PPH3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Serine/threonine-protein phosphatase 4 catalytic subunit; PP4C; EC 3.1.3.16; Phosphatase PP2A-like catalytic subunit PPH3; PPH3; YDR075W |
| UniProt ID | P32345 |
| Protein Refseq | The length of the protein is 308 amino acids long. The sequence is show below: MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQNEVGNAIIPTKKSQMDYFL. |
For Research Use Only | Not For Clinical Use.