Mouse Anti-Yeast TP53 (AA 14-389, clone NW0129) Antibody (MO-NAB-00233W)
Cat: MO-NAB-00233W
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Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus), Yeast |
Clone | NW0129 |
Immunogen | The gel-purified p53-β-galactosidase fusion protein contains murine p53 from aa 14-389 (from the pSV53C cDNA clone). |
Epitope | AA 14-389 |
Format | Liquid or Lyophilized |
Buffer | PBS |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | Protein G purified |
Application Information
Application | WB, ELISA, FC, FC-IC, IF, IHC, IHC-Fr, IHC-P, IP, CyTOF-ready |
Application Notes | WB: 1/1000-1/2000 ELISA: 1/100-1/2000 FC: 1/10-1/1000 IF: 5 ug/ml IHC: 1/250-1/500 IHC-Fr IHC-P: 1/250-1/500 IP: 10 ug/mg |
Target
Introduction | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016] |
Product Overview | Mouse Anti-Yeast TP53 (AA 14-389, clone NW0129) Antibody (MO-NAB-00233W) is a Mouse antibody against the epitope (AA 14-389) of thep53. It can be used for p53 detection in Western Blot, Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Flow Cytometry-IC, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, CyTOF-ready. |
Alternative Names | Tumor Protein P53; Phosphoprotein P53; Antigen NY-CO-13; P53; Transformation-Related Protein 53; Cellular Tumor Antigen P53; Mutant Tumor Protein 53; Li-Fraumeni Syndrome |
Gene ID | 7157 |
UniProt ID | P04637 |
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For Research Use Only | Not For Clinical Use.
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