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- Product Details
|Host species||Mouse (Mus musculus)|
|Species Reactivity||Zebrafish (Danio rerio)|
|Specificity||This antibody binds to Zebrafish acy1.|
|Storage||Store at 4°C: short-term (1-2weeks)|
Store at -20°C: long-term and future use
|Purity||> 90% was determined by SDS-PAGE|
|Purification||Purified with Protein A or G affinity chromatography|
|Application Notes||ELISA: 1:1000-1:3000|
Other applications are to be developed. The optimal dilution should be determined by the end user.
|Introduction||This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.|
|Product Overview||Mouse Anti-Zebrafish acy1 (clone MO63781FYA) Antibody (CBMOAB-63781FYA) is a mouse antibody against acy1. It can be used for acy1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.|
|Alternative Names||Aminoacylase-1; EC 18.104.22.168; N-acyl-L-amino-acid amidohydrolase; acy1; zgc:5560|
|Protein Refseq||The length of the protein is 420 amino acids long.|
The sequence is show below: MLPDKDGLNGGGGVQDGHPAEDPSVTLFREYLRLKTVHPEPDYDAALKFLERMAEELALPMKKVEVCPGRVVAIISWIGSRPELKSVVLNSHTDVVPVYEEHWKHHPFAAVKDADGNIYARGAQDMKSVTIQYIEAIRRLKAAGKRFSRTIHLTFVPDEEVGGHKGMETFVKHPEFQKLNMGFALDEGLANPTNAYTVFYGERNPWWITVRCPGSPGHGSRFVENTAAEKLRRVINSFLEFREKENQRLNTSECFTLGDVTTINMTMVKGGVAYNVVPAEMDVSFDLRIPPTVNLQEFEEKIKVWCREAGEDVTYDFAQKHMDQNLTSTDENDPWWQAFSSTCKAMNMTLKKEIFPAATDSRFIREVGLPAIGFSPMNLTPILLHDHNEYLNEQVFLQGIQVYERLIPALAGVAPLSAEL.
See other products for " acy1 "
|CBMOAB-64838FYA||Mouse Anti-Zebrafish acy1 Antibody (CBMOAB-64838FYA)|
|MO-AB-06978R||Mouse Anti-Cattle ACY1 Antibody (MO-AB-06978R)|
|MO-AB-25680W||Mouse Anti-Chimpanzee ACY1 Antibody (MO-AB-25680W)|
|MO-AB-43579W||Mouse Anti-Horse ACY1 Antibody (MO-AB-43579W)|
|CBMOAB-00367HCB||Mouse Anti-C. elegans ACY1 Antibody (CBMOAB-00367HCB)|
|MO-AB-25679W||Mouse Anti-Chimpanzee ACY1 Antibody (MO-AB-25679W)|
|CBMOAB-64839FYA||Mouse Anti-Zebrafish acy1 Antibody (CBMOAB-64839FYA)|
|CBMOAB-64837FYA||Mouse Anti-Zebrafish acy1 Antibody (CBMOAB-64837FYA)|
|CBMOAB-00921FYA||Mouse Anti-D. melanogaster Acy1 Antibody (CBMOAB-00921FYA)|
|MO-AB-32805H||Mouse Anti-Nile tilapia acy1 Antibody (MO-AB-32805H)|