Mouse Anti-Ago1 Antibody (MOFAB-692W)


Cat: MOFAB-692W
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse
Species ReactivityD. melanogaster, Anopheles, migratory locust, Coptotermes formosanus, Laodelphax striatellus, Neodiprion lecontei, Apolygus lucorum, Dinoponera quadriceps, Nasonia vitripennis, Rhodnius prolixus, Frankliniella occidentalis, Thrips palmi, Neodiprion lecontei, Aedes aegypti, Dinoponera quadriceps, Pogonomyrmex barbatus
FormatLiquid or Lyophilized
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationWB, IHC, IP
Application NotesWB: 1:500-1:2000
IHC: 1:50-1:200
IP: 1:50-1:100
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
Product OverviewThis product is a Mouse antibody against the Ago1. It can be used for Ago1 antibody detection in Western Blot, Immunohistochemistry, Immunoprecipitation.
Alternative NamesProtein argonaute; AGO1; AGO1-RC
UniProt IDQ32KD4
For Research Use Only | Not For Clinical Use.
Online Inquiry